Methadone Hydrochloride Oral Solution Shortage

• • Methadone hydrochloride Intensol oral solution, Hikma, 10 mg/mL concentrate, 30 mL bottle, unflavored, NDC 00054-3553-44
  • Methadone hydrochloride oral solution, Hikma, 10 mg/5 mL, 500 mL bottle, NDC 00054-3556-63
  • Methadone hydrochloride oral solution, Hikma, 10 mg/mL concentrate, 1000 mL bottle, cherry flavor, NDC 00054-0392-68
  • Methadone hydrochloride oral solution, Hikma, 10 mg/mL concentrate, 1000 mL bottle, unflavored, NDC 00054-0391-68
  • Methadone hydrochloride oral solution, Hikma, 5 mg/5 mL, 500 mL bottle, NDC 00054-3555-63

• • Hikma did not provide a reason for the shortage.
  • Mallinckrodt refuses to provide availability information.

• • There is insufficient supply for usual ordering

Estimated Resupply Dates

• • Hikma has methadone 5 mg/5 mL oral solution in 500 mL bottles and 10 mg/5 mL oral solution in 500 mL bottles on back order and the company estimates a release date of mid-August 2025 for the 5 mg/5 mL 500 mL bottles and late-May 2025 for the 10 mg/5 mL 500 mL bottles. The 10 mg/mL concentrated solution in 1,000 mL bottles (cherry flavor and unflavored) is on allocation. Methadone Intensol 10 mg/mL concentrated solution in 30 mL bottles is also on allocation.