Alteplase Injection (Cathflo Activase) Shortage

• • Cathflo Activase intravenous lyophilized powder for injection, Genentech, 2 mg, vial, 1 count, NDC 50242-0041-64

• • On May 28, 2024, Genentech issued a voluntary recall of two batches (batches 3618873 and 3618858) of Cathflo Activase due to defective stoppers. Defective stoppers may not seal properly resulting in potential container closure integrity and sterility concerns. Additional information can be found at https://www.gene.com/download/pdf/Cathflo-Activase_DHCP_Important_Drug_Warning_2024-05-28.pdf.

• • Cathflo Activase intravenous lyophilized powder for injection, Genentech, 2 mg, vial, 10 count, NDC 50242-0041-10

Estimated Resupply Dates

• • Genentech has Cathflo Activase 2 mg vials in single count packages on back order and the company estimates a release date of early- to mid-July 2024.