Zydol XL Interactions
There are 666 drugs known to interact with Zydol XL (tramadol), along with 12 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 313 are major, 351 are moderate, and 2 are minor.
- View all 666 medications that may interact with Zydol XL
- View Zydol XL alcohol/food interactions (1)
- View Zydol XL disease interactions (12)
Most frequently checked interactions
View interaction reports for Zydol XL (tramadol) and the medicines listed below.
- amitriptyline
- apixaban
- baclofen
- Bactrim (sulfamethoxazole / trimethoprim)
- beclomethasone
- Benefiber (guar gum formulation) (guar gum)
- bisacodyl
- Bisolvon Dry (dextromethorphan)
- calcitriol
- Centrum (multivitamin with minerals)
- cisapride
- Cymbalta (duloxetine)
- dantrolene
- doxycycline
- Duogesic (acetaminophen / phenyltoloxamine)
- Eliquis (apixaban)
- Endep (amitriptyline)
- Fentanyl Transdermal System (fentanyl)
- gabapentin
- lactulose
- Lasix (furosemide)
- Levlen (ethinyl estradiol / levonorgestrel)
- Luvox (fluvoxamine)
- magnesium amino acids chelate
- magnesium aspartate
- Mirapex (pramipexole)
- mirtazapine
- Nexium (esomeprazole)
- ondansetron
- oxycodone
Zydol XL alcohol/food interactions
There is 1 alcohol/food interaction with Zydol XL (tramadol).
Zydol XL disease interactions
There are 12 disease interactions with Zydol XL (tramadol) which include:
- gastrointestinal obstruction
- acute alcohol intoxication
- drug dependence
- respiratory depression
- gastrointestinal conditions
- hypoglycemia
- hypotension
- intracranial pressure
- liver disease
- renal dysfunction
- seizure disorders
- suicidal
More about Zydol XL (tramadol)
- Compare alternatives
- Latest FDA alerts (4)
- Side effects
- Dosage information
- During pregnancy
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.