Tramadol Hydrochloride ER Interactions
There are 688 drugs known to interact with Tramadol Hydrochloride ER (tramadol), along with 12 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 313 are major, 373 are moderate, and 2 are minor.
- View all 688 medications that may interact with Tramadol Hydrochloride ER
- View Tramadol Hydrochloride ER alcohol/food interactions (1)
- View Tramadol Hydrochloride ER disease interactions (12)
Most frequently checked interactions
View interaction reports for Tramadol Hydrochloride ER (tramadol) and the medicines listed below.
- acetaminophen
- albuterol
- amlodipine
- aspirin
- atorvastatin
- baclofen
- cyclobenzaprine
- duloxetine
- furosemide
- gabapentin
- hydrochlorothiazide
- ibuprofen
- levothyroxine
- lisinopril
- losartan
- Lyrica (pregabalin)
- melatonin
- meloxicam
- metformin
- omeprazole
- ondansetron
- pantoprazole
- prednisone
- rosuvastatin
- tamsulosin
- tizanidine
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
Tramadol Hydrochloride ER alcohol/food interactions
There is 1 alcohol/food interaction with Tramadol Hydrochloride ER (tramadol).
Tramadol Hydrochloride ER disease interactions
There are 12 disease interactions with Tramadol Hydrochloride ER (tramadol) which include:
- gastrointestinal obstruction
- acute alcohol intoxication
- drug dependence
- respiratory depression
- gastrointestinal conditions
- hypoglycemia
- hypotension
- intracranial pressure
- liver disease
- renal dysfunction
- seizure disorders
- suicidal
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More about Tramadol Hydrochloride ER (tramadol)
- Compare alternatives
- Reviews (14)
- Latest FDA alerts (4)
- Side effects
- Dosage information
- During pregnancy
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.