Drug Interactions between tinidazole and Xermelo

Consumption of alcoholic beverages or products containing alcohol or propylene glycol during treatment with tinidazole may occasionally trigger a reaction in some patients similar to the disulfiram reaction, which includes unpleasant effects such as flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion. Rarely, more severe reactions may include abnormal heart rhythm, heart attack, heart failure, unconsciousness, convulsions, and even death. Patients treated with tinidazole should avoid using any products containing alcohol or propylene glycol during and for up to 3 days until after completion of therapy. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food increases the absorption of telotristat ethyl. To ensure adequate blood levels of the medication, telotristat ethyl should be administered with food or a meal.