Nucynta Interactions
There are 398 drugs known to interact with Nucynta (tapentadol), along with 14 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 187 are major, 210 are moderate, and 1 is minor.
- View all 398 medications that may interact with Nucynta
- View Nucynta alcohol/food interactions (1)
- View Nucynta disease interactions (14)
Most frequently checked interactions
View interaction reports for Nucynta (tapentadol) and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- aspirin
- atorvastatin
- baclofen
- clonazepam
- cyclobenzaprine
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- gabapentin
- hydrochlorothiazide
- hydroxyzine
- levothyroxine
- lisinopril
- Lyrica (pregabalin)
- meloxicam
- metformin
- methocarbamol
- Nexium (esomeprazole)
- omeprazole
- oxycodone
- pantoprazole
- prednisone
- Synthroid (levothyroxine)
- tizanidine
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
Nucynta alcohol/food interactions
There is 1 alcohol/food interaction with Nucynta (tapentadol).
Nucynta disease interactions
There are 14 disease interactions with Nucynta (tapentadol) which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- biliary tract disease
Report options
QR code containing a link to this page
More about Nucynta (tapentadol)
- Nucynta consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (279)
- Drug images
- Latest FDA alerts (1)
- Side effects
- Dosage information
- During pregnancy
- Support group
- FDA approval history
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
