St. john's wort Drug Interactions
Currently displaying a list of 623 drugs known to interact with st. john's wort.
- 276 major drug interactions
- 320 moderate drug interactions
- 27 minor drug interactions
Medications known to interact with st. john's wort
Note: Showing generic names only.
5
A
- abemaciclib
- abiraterone
- abrocitinib
- acalabrutinib
- acetylcarbromal
- acrivastine
- adagrasib
- afatinib
- aldesleukin
- alfentanil
- aliskiren
- allopurinol
- almotriptan
- alpelisib
- alprazolam
- aminolevulinic acid
- aminolevulinic acid topical
- aminophylline
- amiodarone
- amitriptyline
- amlodipine
- amoxapine
- amphetamine
- amprenavir
- anisindione
- apixaban
- apomorphine
- apraclonidine ophthalmic
- apremilast
- aprepitant
- aprocitentan
- aripiprazole
- armodafinil
- asciminib
- asenapine
- atazanavir
- atogepant
- atorvastatin
- avacopan
- avanafil
- avapritinib
- avatrombopag
- axitinib
- azelastine nasal
B
- baclofen
- bedaquiline
- belumosudil
- benzphetamine
- benztropine
- berotralstat
- betrixaban
- bexagliflozin
- bexarotene
- binimetinib
- boceprevir
- bortezomib
- bosentan
- bosutinib
- brexanolone
- brexpiprazole
- brigatinib
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromocriptine
- brompheniramine
- budesonide
- buprenorphine
- buspirone
- busulfan
- butabarbital
- butalbital
- butorphanol
C
- cabazitaxel
- cabozantinib
- calcifediol
- calcitriol
- canagliflozin
- cannabidiol
- cannabis
- capivasertib
- capmatinib
- carbamazepine
- carbetapentane
- carbinoxamine
- carbonyl iron
- cariprazine
- carisoprodol
- caspofungin
- celecoxib
- cenobamate
- ceritinib
- cetirizine
- chlophedianol
- chloral hydrate
- chlordiazepoxide
- chlormezanone
- chloroquine
- chlorotrianisene
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorzoxazone
- cholecalciferol
- cilostazol
- citalopram
- cladribine
- clarithromycin
- clemastine
- clindamycin
- clobazam
- clomipramine
- clonidine
- clorazepate
- clozapine
- cobicistat
- cobimetinib
- codeine
- conjugated estrogens
- copanlisib
- crizotinib
- cyclizine
- cyclobenzaprine
- cyclophosphamide
- cyclosporine
- cyproheptadine
D
- dabigatran
- dabrafenib
- daclatasvir
- dantrolene
- dapsone topical
- daridorexant
- darifenacin
- darolutamide
- darunavir
- dasatinib
- deflazacort
- delavirdine
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexbrompheniramine
- dexfenfluramine
- dexlansoprazole
- dexmedetomidine
- dextroamphetamine
- dextromethorphan
- dezocine
- diazepam
- dicumarol
- difelikefalin
- digoxin
- dihydroergotamine
- dihydrotachysterol
- diltiazem
- dimenhydrinate
- diphenhydramine
- divalproex sodium
- docetaxel
- dolasetron
- dolutegravir
- donepezil
- doravirine
- doxepin
- doxepin topical
- doxercalciferol
- doxorubicin
- doxorubicin liposomal
- doxylamine
- dronabinol
- dronedarone
- droperidol
- drospirenone
- duloxetine
- duvelisib
E
- edoxaban
- efavirenz
- elacestrant
- elagolix
- eletriptan
- eliglustat
- elvitegravir
- encorafenib
- enfortumab vedotin
- entrectinib
- enzalutamide
- eplerenone
- eravacycline
- erdafitinib
- ergocalciferol
- ergonovine
- ergotamine
- erlotinib
- escitalopram
- eslicarbazepine
- esomeprazole
- estazolam
- esterified estrogens
- estradiol
- estradiol topical
- estrone
- estropipate
- eszopiclone
- ethanol
- ethinyl estradiol
- ethosuximide
- ethotoin
- etonogestrel
- etoposide
- etravirine
- everolimus
- exemestane
- ezogabine
F
- fedratinib
- felbamate
- felodipine
- fenfluramine
- fentanyl
- ferric maltol
- ferrous fumarate
- ferrous gluconate
- ferrous sulfate
- fesoterodine
- fexinidazole
- fexofenadine
- finerenone
- flavoxate
- flibanserin
- fluoxetine
- fluphenazine
- flurazepam
- fluvoxamine
- fosamprenavir
- fosaprepitant
- fospropofol
- fostamatinib
- fostemsavir
- frovatriptan
- fruquintinib
- furazolidone
- futibatinib
G
- gabapentin
- gabapentin enacarbil
- ganaxolone
- gefitinib
- gepirone
- gilteritinib
- glasdegib
- granisetron
- guanfacine
H
- halazepam
- haloperidol
- heme iron polypeptide
- heroin
- hydrocodone
- hydromorphone
- hydroxychloroquine
- hydroxyprogesterone
- hydroxyzine
I
- ibrexafungerp
- ibrutinib
- idelalisib
- ifosfamide
- iloperidone
- imatinib
- imipramine
- indinavir
- infigratinib
- iobenguane I 123
- iobenguane I 131
- ioflupane I 123
- irinotecan
- irinotecan liposomal
- iron bisglycinate
- iron polysaccharide
- iron protein succinylate
- isavuconazonium
- isocarboxazid
- isoniazid
- isradipine
- istradefylline
- itraconazole
- ivabradine
- ivacaftor
- ivosidenib
- ixabepilone
- ixazomib
K
L
- lacosamide
- lansoprazole
- lapatinib
- larotrectinib
- lasmiditan
- lazertinib
- lefamulin
- lemborexant
- lenacapavir
- leniolisib
- lesinurad
- letermovir
- letrozole
- levamlodipine
- levetiracetam
- levobupivacaine
- levocetirizine
- levodopa
- levoketoconazole
- levomethadyl acetate
- levomilnacipran
- levonorgestrel
- levorphanol
- levothyroxine
- levothyroxine / liothyronine
- lidocaine
- linagliptin
- linezolid
- liothyronine
- liotrix
- lisdexamfetamine
- lithium
- lofexidine
- lonafarnib
- lorazepam
- lorcaserin
- lorlatinib
- lovastatin
- loxapine
- lumateperone
- lurasidone
- lurbinectedin
M
- macimorelin
- macitentan
- maprotiline
- maraviroc
- maribavir
- mavacamten
- mavorixafor
- mazindol
- medroxyprogesterone
- mefloquine
- megestrol
- melatonin
- meperidine
- mephenytoin
- mephobarbital
- meprobamate
- mesoridazine
- metaxalone
- methadone
- methamphetamine
- methocarbamol
- methohexital
- methoxsalen
- methsuximide
- methyl aminolevulinate topical
- methylene blue
- methylergonovine
- methysergide maleate
- metyrosine
- mibefradil
- midazolam
- midostaurin
- mifepristone
- milnacipran
- mirabegron
- mirtazapine
- mitapivat
- mitotane
- mobocertinib
- modafinil
- molindone
- montelukast
- morphine
- morphine liposomal
- multivitamin with iron
- multivitamin with iron and fluoride
- multivitamin with minerals
- multivitamin, prenatal
N
- nabilone
- nalbuphine
- naldemedine
- naloxegol
- naratriptan
- nefazodone
- nelfinavir
- neratinib
- nevirapine
- nicardipine
- nifedipine
- nilotinib
- nimodipine
- nintedanib
- nirogacestat
- nitisinone
- norethindrone
- norgestrel
- nortriptyline
O
- olanzapine
- olaparib
- oliceridine
- olopatadine nasal
- olutasidenib
- omaveloxolone
- omeprazole
- ondansetron
- opicapone
- opium
- orphenadrine
- osilodrostat
- osimertinib
- ospemifene
- oxazepam
- oxcarbazepine
- oxtriphylline
- oxycodone
- oxymorphone
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- paliperidone
- palonosetron
- palovarotene
- panobinostat
- pantoprazole
- paraldehyde
- paramethadione
- paricalcitol
- paroxetine
- pazopanib
- pemigatinib
- pentazocine
- pentobarbital
- perampanel
- pergolide
- perphenazine
- pexidartinib
- phenacemide
- phenelzine
- phenobarbital
- phensuximide
- phentermine
- phenytoin
- pimavanserin
- pimozide
- pirtobrutinib
- pitolisant
- polatuzumab vedotin
- pomalidomide
- ponatinib
- ponesimod
- porfimer
- pralsetinib
- pramipexole
- praziquantel
- pregabalin
- pretomanid
- primidone
- procarbazine
- prochlorperazine
- progesterone
- progesterone topical
- promazine
- promethazine
- propiomazine
- propofol
- propoxyphene
- protriptyline
- pyrilamine
Q
R
- rabeprazole
- raltegravir
- ramelteon
- ranolazine
- rasagiline
- regorafenib
- relugolix
- remdesivir
- remifentanil
- remimazolam
- repaglinide
- repotrectinib
- ribociclib
- rilpivirine
- rimegepant
- riociguat
- ripretinib
- risperidone
- ritlecitinib
- ritonavir
- rivaroxaban
- rizatriptan
- roflumilast
- rolapitant
- romidepsin
- ropinirole
- rotigotine
- rucaparib
- rufinamide
- ruxolitinib
S
- safinamide
- saquinavir
- saxagliptin
- scopolamine
- secobarbital
- seladelpar
- selegiline
- selinexor
- selpercatinib
- selumetinib
- sertraline
- sevoflurane
- sibutramine
- sildenafil
- silodosin
- simeprevir
- simvastatin
- siponimod
- sirolimus
- sirolimus protein-bound
- sodium oxybate
- sofosbuvir
- solifenacin
- sonidegib
- sorafenib
- sotagliflozin
- sotorasib
- sparsentan
- stiripentol
- sufentanil
- sumatriptan
- sunitinib
- suvorexant
T
- tacrolimus
- tadalafil
- tamoxifen
- tapentadol
- tasimelteon
- tazemetostat
- telaprevir
- telithromycin
- temazepam
- temsirolimus
- teniposide
- tenofovir alafenamide
- tenofovir disoproxil
- tepotinib
- teriflunomide
- tetrabenazine
- thalidomide
- theophylline
- thiopental
- thioridazine
- thiotepa
- thiothixene
- thyroid desiccated
- tiagabine
- ticagrelor
- tipranavir
- tisotumab vedotin
- tivozanib
- tizanidine
- tofacitinib
- tolvaptan
- toremifene
- trabectedin
- tramadol
- tranylcypromine
- trazodone
- treprostinil
- tretinoin
- triazolam
- trifluoperazine
- triflupromazine
- trimeprazine
- trimethadione
- trimethobenzamide
- trimethoprim
- trimipramine
- tripelennamine
- triprolidine
- tryptophan
- tucatinib
U
V
- valbenazine
- valerian
- valproic acid
- vandetanib
- vemurafenib
- venetoclax
- venlafaxine
- verteporfin
- vigabatrin
- vilazodone
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- voclosporin
- vonoprazan
- vorapaxar
- voriconazole
- vortioxetine
- voxelotor
W
Z
St. john's wort alcohol/food interactions
There is 1 alcohol/food interaction with st. john's wort.
More about st. john's wort
- st. john's wort consumer information
- Check interactions
- Compare alternatives
- Reviews (144)
- Side effects
- Drug class: herbal products
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.