Phenergan Interactions
There are 688 drugs known to interact with Phenergan (promethazine), along with 13 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 94 are major, 579 are moderate, and 15 are minor.
- View all 688 medications that may interact with Phenergan
- View Phenergan alcohol/food interactions (2)
- View Phenergan disease interactions (13)
Most frequently checked interactions
View interaction reports for Phenergan (promethazine) and the medicines listed below.
- albuterol
- Ambien (zolpidem)
- aspirin
- Ativan (lorazepam)
- baclofen
- Benadryl (diphenhydramine)
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- gabapentin
- ibuprofen
- Klonopin (clonazepam)
- levothyroxine
- lisinopril
- Lyrica (pregabalin)
- melatonin
- metformin
- Norco (acetaminophen / hydrocodone)
- omeprazole
- oxycodone
- prednisone
- Protonix (pantoprazole)
- Synthroid (levothyroxine)
- tizanidine
- Topamax (topiramate)
- tramadol
- trazodone
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zyrtec (cetirizine)
Phenergan alcohol/food interactions
There are 2 alcohol/food interactions with Phenergan (promethazine).
Phenergan disease interactions
There are 13 disease interactions with Phenergan (promethazine) which include:
- acute alcohol intoxication
- CNS depression
- hematologic toxicity
- hypotension
- liver disease
- antidopaminergic effects 1
- asthma
- anticholinergic effects
- asthma/COPD
- breast cancer
- NMS
- seizure disorders
- antidopaminergic effects 2
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More about Phenergan (promethazine)
- Phenergan consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (151)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Generic availability
- Support group
- Drug class: antihistamines
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
