Phenergan Interactions
There are 689 drugs known to interact with Phenergan (promethazine), along with 18 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 92 are major, 583 are moderate, and 14 are minor.
- View all 689 medications that may interact with Phenergan
- View Phenergan alcohol/food interactions (1)
- View Phenergan disease interactions (18)
Most frequently checked interactions
View interaction reports for Phenergan (promethazine) and the medicines listed below.
- albuterol
- Ambien (zolpidem)
- aspirin
- Ativan (lorazepam)
- baclofen
- Benadryl (diphenhydramine)
- clonazepam
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- gabapentin
- ibuprofen
- Klonopin (clonazepam)
- levothyroxine
- lisinopril
- Lyrica (pregabalin)
- metformin
- Norco (acetaminophen / hydrocodone)
- omeprazole
- oxycodone
- prednisone
- Protonix (pantoprazole)
- Synthroid (levothyroxine)
- tizanidine
- Topamax (topiramate)
- tramadol
- trazodone
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zyrtec (cetirizine)
Phenergan alcohol/food interactions
There is 1 alcohol/food interaction with Phenergan (promethazine).
Phenergan disease interactions
There are 18 disease interactions with Phenergan (promethazine) which include:
- acute alcohol intoxication
- cardiovascular disease
- CNS depression
- head injury
- antidopaminergic effects 1
- asthma
- anticholinergic effects
- asthma/COPD
- breast cancer
- dystonic reactions
- hematologic toxicity
- liver disease
- NMS
- parkinsonism
- renal dysfunction
- seizure disorders
- tardive dyskinesia
- antidopaminergic effects 2
More about Phenergan (promethazine)
- Phenergan consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (148)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Generic availability
- Support group
- Drug class: antihistamines
- Breastfeeding
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.