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Drug Interactions between Poly-Tussin EX Syrup and somatrem

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

somatrem dihydrocodeine

Applies to: somatrem and Poly-Tussin EX Syrup (dihydrocodeine / guaifenesin / phenylephrine)

Somatrem may reduce the blood levels and effects of dihydrocodeine. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Let your doctor know if dihydrocodeine becomes less effective or is no longer controlling your symptoms. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Drug and food interactions

Moderate

phenylephrine food

Applies to: Poly-Tussin EX Syrup (dihydrocodeine / guaifenesin / phenylephrine)

Both phenylephrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer