Drug Interactions between penicillin g benzathine / procaine penicillin and Urobiotic-250
This report displays the potential drug interactions for the following 2 drugs:
- penicillin g benzathine/procaine penicillin
- Urobiotic-250 (oxytetracycline/phenazopyridine/sulfamethizole)
Interactions between your drugs
phenazopyridine procaine penicillin
Applies to: Urobiotic-250 (oxytetracycline / phenazopyridine / sulfamethizole) and penicillin g benzathine / procaine penicillin
Medications containing local anesthetics such as procaine penicillin may cause methemoglobinemia, a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood. The risk is increased when combined with other medications that can also induce methemoglobinemia such as phenazopyridine. Individuals may be more susceptible to developing methemoglobinemia during treatment with these medications if they are very young (especially neonates and infants) or have diseases of the heart or lungs, certain genetic predispositions, or glucose-6-phosphate dehydrogenase deficiency. Close medical supervision is necessary when medications that can cause methemoglobinemia are used together. Signs and symptoms of methemoglobinemia may occur immediately or hours after treatment. Patients or their caregivers should seek immediate medical attention if they develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
sulfamethizole procaine penicillin
Applies to: Urobiotic-250 (oxytetracycline / phenazopyridine / sulfamethizole) and penicillin g benzathine / procaine penicillin
Medications containing local anesthetics such as procaine penicillin may cause methemoglobinemia, a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood. The risk is increased when combined with other medications that can also induce methemoglobinemia such as sulfamethizole. Individuals may be more susceptible to developing methemoglobinemia during treatment with these medications if they are very young (especially neonates and infants) or have diseases of the heart or lungs, certain genetic predispositions, or glucose-6-phosphate dehydrogenase deficiency. Close medical supervision is necessary when medications that can cause methemoglobinemia are used together. Signs and symptoms of methemoglobinemia may occur immediately or hours after treatment. Patients or their caregivers should seek immediate medical attention if they develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
oxytetracycline procaine penicillin
Applies to: Urobiotic-250 (oxytetracycline / phenazopyridine / sulfamethizole) and penicillin g benzathine / procaine penicillin
Talk to your doctor before using oxytetracycline together with procaine penicillin. Combining these medications may reduce the effectiveness of procaine penicillin. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
oxytetracycline penicillin G benzathine
Applies to: Urobiotic-250 (oxytetracycline / phenazopyridine / sulfamethizole) and penicillin g benzathine / procaine penicillin
Talk to your doctor before using oxytetracycline together with penicillin G benzathine. Combining these medications may reduce the effectiveness of penicillin G benzathine. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
oxytetracycline food
Applies to: Urobiotic-250 (oxytetracycline / phenazopyridine / sulfamethizole)
Do not take iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking oxytetracycline. These products can make oxytetracycline less effective in treating your infection. Do not take oxytetracycline with milk or other dairy products, unless your doctor has told you to. Dairy products can make it harder for your body to absorb the medication.
oxytetracycline food
Applies to: Urobiotic-250 (oxytetracycline / phenazopyridine / sulfamethizole)
Iron can bind to oxytetracycline in the gastrointestinal tract, which may prevent their absorption into the bloodstream and possibly reduce their effectiveness. To avoid or minimize the interaction, iron-containing medications and oxytetracycline should preferably be taken at least three to four hours apart in most cases. Talk to your doctor if you have any questions or concerns, or if you have trouble separating the dosing times. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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