Drug Interactions between omeprazole and peppermint oil
This report displays the potential drug interactions for the following 2 drugs:
- omeprazole
- peppermint oil
Interactions between your drugs
omeprazole peppermint oil
Applies to: omeprazole and peppermint oil
The following interaction applies to enteric-coated, gastro-resistant formulations of peppermint oil (usually delayed or sustained release capsules):
Acid-lowering agents like omeprazole may disrupt the release mechanism of delayed or extended release formulations of peppermint oil by causing premature dissolution of the enteric coating in the stomach, resulting in early release of the peppermint oil. This can lead to gastrointestinal irritation such as heartburn, indigestion, nausea and vomiting, as well as reduced effectiveness of the medication. If you are taking an enteric-coated, gastro-resistant formulation of peppermint oil and require the use of antacids (medications that neutralize stomach acid such as Alka-Seltzer, Gaviscon, Gelusil, Maalox, Milk of Magnesia, Mylanta, Rolaids, and Tums), you should separate their times of administration by at least 2 hours. Acid suppressants such as cimetidine (Tagamet), famotidine (Pepcid), ranitidine (Zantac), esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), and pantoprazole (Protonix) should generally be avoided if possible. Talk to your doctor or pharmacist if you have questions on how to take peppermint oil or any of your other medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
peppermint oil food
Applies to: peppermint oil
The following applies to enteric-coated, gastro-resistant formulations of peppermint oil (usually delayed or sustained release capsules):
Administration with food may disrupt the release mechanism of delayed or extended release formulations of peppermint oil by causing premature dissolution of the enteric coating in the stomach, resulting in early release of the peppermint oil. This can lead to gastrointestinal irritation such as heartburn, indigestion, nausea and vomiting, as well as reduced effectiveness of the medication. Enteric-coated, gastro-resistant formulations of peppermint oil should not be taken immediately after eating. These products should preferably be taken 30 to 90 minutes before a meal with water. The labeling for the specific product should be consulted for administration recommendations and other guidance. Talk to your doctor or pharmacist if you have questions on how to take peppermint oil or any of your other medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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