Drug Interactions between metoprolol and Symbicort

Budesonide may reduce the effects of metoprolol in lowering blood pressure. The interaction is most likely to occur when budesonide is used for more than a week, since prolonged use can cause sodium and water retention. Let your doctor know if you experience sudden, unexplained weight gain or swelling of the hands, ankles, or feet. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Using metoprolol together with formoterol may reduce the benefits of both medications, since they have opposing effects in the body. In addition, metoprolol can sometimes cause narrowing of the airways, which may worsen your breathing problems or trigger severe asthmatic attacks. You may not be able to use metoprolol if you have frequent asthma attacks or severe asthma or COPD (chronic obstructive pulmonary disease), or you may need a dose adjustment and more frequent monitoring of your lung function to safely use both medications. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. Let your doctor know if you experience wheezing, shortness of breath, chest tightness, or other breathing difficulties during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Information for this minor interaction is available on the professional version.