Otrexup Interactions
There are 718 drugs known to interact with Otrexup (methotrexate), along with 5 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 144 are major, 559 are moderate, and 15 are minor.
- View all 718 medications that may interact with Otrexup
- View Otrexup alcohol/food interactions (3)
- View Otrexup disease interactions (5)
Most frequently checked interactions
View interaction reports for Otrexup (methotrexate) and the medicines listed below.
- amlodipine
- amoxicillin
- atenolol
- atorvastatin
- Benadryl (diphenhydramine)
- Cymbalta (duloxetine)
- doxycycline
- Enbrel (etanercept)
- Flexeril (cyclobenzaprine)
- folic acid
- gabapentin
- Humira (adalimumab)
- hydroxychloroquine
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- magnesium glycinate
- meloxicam
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- omeprazole
- ondansetron
- Orencia (abatacept)
- oxycodone
- pantoprazole
- Plaquenil (hydroxychloroquine)
- prednisone
- Singulair (montelukast)
- tizanidine
- tramadol
- Vitamin D3 (cholecalciferol)
Otrexup alcohol/food interactions
There are 3 alcohol/food interactions with Otrexup (methotrexate).
Otrexup disease interactions
There are 5 disease interactions with Otrexup (methotrexate) which include:
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More about Otrexup (methotrexate)
- Otrexup consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (2)
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: antimetabolites
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.