Loperamide/simethicone Interactions
There are 357 drugs known to interact with loperamide/simethicone, along with 4 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 44 are major, 312 are moderate, and 1 is minor.
- View all 357 medications that may interact with loperamide/simethicone
- View loperamide/simethicone alcohol/food interactions (1)
- View loperamide/simethicone disease interactions (4)
Most frequently checked interactions
View interaction reports for loperamide / simethicone and the medicines listed below.
- Alcohol (contained in alcoholic beverages) (ethanol)
- Allegra (fexofenadine)
- Aspirin Low Strength (aspirin)
- Ativan (lorazepam)
- Augmentin (amoxicillin / clavulanate)
- Benadryl (diphenhydramine)
- Claritin (loratadine)
- CoQ10 (ubiquinone)
- Cymbalta (duloxetine)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Jardiance (empagliflozin)
- Lipitor (atorvastatin)
- Metoprolol Succinate ER (metoprolol)
- Mucinex (guaifenesin)
- Norco (acetaminophen / hydrocodone)
- Omega-3 (omega-3 polyunsaturated fatty acids)
- Paxlovid (nirmatrelvir / ritonavir)
- Pepto-Bismol (bismuth subsalicylate)
- Probiotic Formula (bifidobacterium infantis / lactobacillus acidophilus)
- Synthroid (levothyroxine)
- Tums Extra Strength 750 (calcium carbonate)
- Tylenol (acetaminophen)
- Tylenol Extra Strength (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Zofran (ondansetron)
- Zyrtec (cetirizine)
Loperamide/simethicone alcohol/food interactions
There is 1 alcohol/food interaction with loperamide / simethicone.
Loperamide/simethicone disease interactions
There are 4 disease interactions with loperamide / simethicone which include:
More about loperamide / simethicone
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- During pregnancy
- Drug class: antidiarrheals
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.