Kyleena Interactions
There are 258 drugs known to interact with Kyleena (levonorgestrel), along with 12 disease interactions, and 5 alcohol/food interactions. Of the total drug interactions, 54 are major, 189 are moderate, and 15 are minor.
- View all 258 medications that may interact with Kyleena
- View Kyleena alcohol/food interactions (5)
- View Kyleena disease interactions (12)
Most frequently checked interactions
View interaction reports for Kyleena (levonorgestrel) and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- albuterol
- Benadryl (diphenhydramine)
- bupropion
- cyclobenzaprine
- famotidine
- fluoxetine
- gabapentin
- hydroxyzine
- ibuprofen
- lamotrigine
- levothyroxine
- magnesium glycinate
- melatonin
- metformin
- omeprazole
- ondansetron
- prednisone
- propranolol
- Prozac (fluoxetine)
- sertraline
- spironolactone
- topiramate
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Wellbutrin XL (bupropion)
- Zyrtec (cetirizine)
Kyleena alcohol/food interactions
There are 5 alcohol/food interactions with Kyleena (levonorgestrel).
Kyleena disease interactions
There are 12 disease interactions with Kyleena (levonorgestrel) which include:
- abnormal genital bleeding
- hepatic neoplasms
- breast malignancy
- liver disease
- depression
- fluid retention
- glucose intolerance
- retinal thrombosis
- thyroid function tests
- cardiovascular disease
- hyperlipidemia
- weight gain
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More about Kyleena (levonorgestrel)
- Kyleena consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (1,637)
- Drug images
- Latest FDA alerts (1)
- Side effects
- Dosage information
- During pregnancy
- Support group
- FDA approval history
- Drug class: contraceptives
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
