Orkambi Interactions
There are 572 drugs known to interact with Orkambi (ivacaftor/lumacaftor), along with 6 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 256 are major, 303 are moderate, and 13 are minor.
- View all 572 medications that may interact with Orkambi
- View Orkambi alcohol/food interactions (2)
- View Orkambi disease interactions (6)
Most frequently checked interactions
View interaction reports for Orkambi (ivacaftor / lumacaftor) and the medicines listed below.
- albuterol
- amitriptyline
- amoxicillin
- azithromycin
- Cayston (aztreonam)
- ciprofloxacin
- clofazimine
- Corifact (factor XIII)
- Creon (pancrelipase)
- Dulera (formoterol / mometasone)
- Humalog (insulin lispro)
- Hyper-Sal (sodium chloride)
- ibuprofen
- Kalydeco (ivacaftor)
- lansoprazole
- meropenem
- MiraLAX (polyethylene glycol 3350)
- Nucala (mepolizumab)
- omeprazole
- oxycodone
- prednisone
- ProAir HFA (albuterol)
- Pulmozyme (dornase alfa)
- Qvar RediHaler (beclomethasone)
- Remeron (mirtazapine)
- Symbicort (budesonide / formoterol)
- tobramycin
- Trikafta (elexacaftor / ivacaftor / tezacaftor)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
Orkambi alcohol/food interactions
There are 2 alcohol/food interactions with Orkambi (ivacaftor / lumacaftor).
Orkambi disease interactions
There are 6 disease interactions with Orkambi (ivacaftor / lumacaftor) which include:
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More about Orkambi (ivacaftor / lumacaftor)
- Orkambi consumer information
- Compare alternatives
- Pricing & coupons
- Drug images
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: CFTR combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
