Ibuprofen/phenylephrine Interactions
There are 557 drugs known to interact with ibuprofen/phenylephrine, along with 17 disease interactions, and 4 alcohol/food interactions. Of the total drug interactions, 123 are major, 417 are moderate, and 17 are minor.
- View all 557 medications that may interact with ibuprofen/phenylephrine
- View ibuprofen/phenylephrine alcohol/food interactions (4)
- View ibuprofen/phenylephrine disease interactions (17)
Most frequently checked interactions
View interaction reports for ibuprofen / phenylephrine and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Aspirin Low Strength (aspirin)
- Bayer Aspirin (aspirin)
- Claritin (loratadine)
- Cymbalta (duloxetine)
- Effexor XR (venlafaxine)
- Entresto (sacubitril / valsartan)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Klonopin (clonazepam)
- Levoxyl (levothyroxine)
- Metoprolol Tartrate (metoprolol)
- Mucinex (guaifenesin)
- Nasonex (mometasone nasal)
- Nexium 24HR (esomeprazole)
- Os-Cal Calcium+D3 (calcium / vitamin d)
- Ozempic (semaglutide)
- Phazyme (simethicone)
- Phenylephrine HD (hydrocodone / phenylephrine)
- Prilosec (omeprazole)
- Rhinocort Allergy (budesonide nasal)
- Super B Complex (multivitamin)
- Tramal (tramadol)
- Tylenol Extra Strength (acetaminophen)
- Tylenol with Codeine #3 (acetaminophen / codeine)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Xigduo XR (dapagliflozin / metformin)
Ibuprofen/phenylephrine alcohol/food interactions
There are 4 alcohol/food interactions with ibuprofen / phenylephrine.
Ibuprofen/phenylephrine disease interactions
There are 17 disease interactions with ibuprofen / phenylephrine which include:
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- cardiovascular disease
- PKU
- anemia
- heart failure
- hepatotoxicity
- hyperkalemia
- hypertension
- platelet aggregation inhibition
- BPH
- diabetes
- glaucoma
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More about ibuprofen / phenylephrine
- ibuprofen/phenylephrine consumer information
- Compare alternatives
- Imprints, shape & color data
- Side effects
- Drug class: upper respiratory combinations
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.