Drug Interactions between Probenecid and Colchicine and hyoscyamine / methenamine / methylene blue / phenyl salicylate
This report displays the potential drug interactions for the following 2 drugs:
- Probenecid and Colchicine (colchicine/probenecid)
- hyoscyamine/methenamine/methylene blue/phenyl salicylate
Interactions between your drugs
probenecid phenyl salicylate
Applies to: Probenecid and Colchicine (colchicine / probenecid) and hyoscyamine / methenamine / methylene blue / phenyl salicylate
Talk to your doctor before using probenecid together with phenyl salicylate. Depending on the dose and how frequently phenyl salicylate is taken, it may interfere with the action of probenecid and reduce its effectiveness in treating gout or gouty arthritis. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
colchicine food
Applies to: Probenecid and Colchicine (colchicine / probenecid)
Drinking large amounts of grapefruit juice can increase your blood levels of colchicine to dangerous levels. You should avoid the consumption of grapefruit or grapefruit juice during treatment with colchicine. Let your doctor know if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet, as these may be early symptoms of colchicine toxicity.
hyoscyamine food
Applies to: hyoscyamine / methenamine / methylene blue / phenyl salicylate
Ask your doctor before using hyoscyamine together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking hyoscyamine. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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