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Drug Interactions between fluorouracil and sars-cov-2 mrna (tozinameran) vaccine

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

fluorouracil SARS-CoV-2 mRNA (tozinameran) vaccine

Applies to: fluorouracil and sars-cov-2 mrna (tozinameran) vaccine

If you are currently being treated or have recently been treated with fluorouracil, you should let your doctor know before receiving SARS-CoV-2 mRNA (tozinameran) vaccine. Depending on the dose and length of time you have been on fluorouracil, you may have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of fluorouracil therapy. If you have recently been vaccinated with SARS-CoV-2 mRNA (tozinameran) vaccine, your doctor may choose to postpone treatment with fluorouracil for a couple of weeks or more. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Major

fluorouracil food

Applies to: fluorouracil

Products containing folic acid may increase the effects of fluorouracil. You may be more likely to develop serious side effects such as anemia, bleeding problems, infections, and nerve damage when these medications are used together. Contact your doctor if you experience severe nausea and vomiting, diarrhea, paleness of skin, fatigue, dizziness, fainting, unusual bleeding or bruising, blood in the stools, fever, chills, body aches, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling in your hands and feet. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer