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Drug Interactions between ezetimibe and Nubeqa

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

ezetimibe darolutamide

Applies to: ezetimibe and Nubeqa (darolutamide)

Darolutamide may increase the blood levels and effects of ezetimibe. This may increase your chances of experiencing serious, but relatively rare side effects such as liver damage or a condition that involves the breakdown of skeletal muscle tissue known as rhabdomyolysis. You may need more frequent monitoring by your healthcare provider to safely use both medications. Let your doctor know immediately if you have unexplained muscle pain, tenderness, or weakness while taking these medications, especially if these symptoms are accompanied by fever or dark colored urine. You should also seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, as these may be signs and symptoms of liver damage. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

darolutamide food

Applies to: Nubeqa (darolutamide)

Food helps with the absorption of darolutamide into the blood stream. You should take this medication with food as directed.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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