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Drug Interactions between donepezil and trospium

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

donepezil trospium

Applies to: donepezil and trospium

Using donepezil together with trospium may decrease the benefits of donepezil in the treatment of dementia. Donepezil may also counteract the benefit of trospium. Trospium should generally be avoided in patients with Alzheimer's disease or other cognitive problems. Trospium may also adversely affect elderly patients by producing symptoms ranging from mild thinking impairment to delirium. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor.

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Drug and food interactions

Moderate

trospium food

Applies to: trospium

Trospium should be taken on an empty stomach 1 hour before or 2 hours after a meal unless otherwise directed by your doctor. You may experience reduced absorption of trospium in the presence of food. This will make it easier for your body to absorb the medication.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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