Pennsaid Interactions
There are 128 drugs known to interact with Pennsaid (diclofenac topical), along with 4 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 9 are major, and 119 are moderate.
- View all 128 medications that may interact with Pennsaid
- View Pennsaid alcohol/food interactions (1)
- View Pennsaid disease interactions (4)
Most frequently checked interactions
View interaction reports for Pennsaid (diclofenac topical) and the medicines listed below.
- amlodipine
- aspirin
- atorvastatin
- baclofen
- Benadryl (diphenhydramine)
- Celebrex (celecoxib)
- cyclobenzaprine
- Cymbalta (duloxetine)
- folic acid
- gabapentin
- ibuprofen
- levothyroxine
- lisinopril
- Lyrica (pregabalin)
- magnesium oxide
- melatonin
- meloxicam
- metformin
- omeprazole
- ondansetron
- oxycodone
- pantoprazole
- prednisone
- Synthroid (levothyroxine)
- tizanidine
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
Pennsaid alcohol/food interactions
There is 1 alcohol/food interaction with Pennsaid (diclofenac topical).
Pennsaid disease interactions
There are 4 disease interactions with Pennsaid (diclofenac topical) which include:
Report options
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More about Pennsaid (diclofenac topical)
- Pennsaid consumer information
- Compare alternatives
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- Reviews (53)
- Latest FDA alerts (2)
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: topical non-steroidal anti-inflammatories
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.