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Prolia Interactions

There are 298 drugs known to interact with Prolia (denosumab), along with 2 disease interactions. Of the total drug interactions, 5 are major, and 293 are moderate.

Does Prolia interact with my other drugs?

Enter medications to view a detailed interaction report using our Drug Interaction Checker.

Most frequently checked interactions

View interaction reports for Prolia (denosumab) and the medicines listed below.

Prolia disease interactions

There are 2 disease interactions with Prolia (denosumab) which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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