Chlorothiazide/methyldopa Interactions
There are 565 drugs known to interact with chlorothiazide/methyldopa, along with 19 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 33 are major, 498 are moderate, and 34 are minor.
- View chlorothiazide/methyldopa alcohol/food interactions (3)
- View chlorothiazide/methyldopa disease interactions (19)
Medications known to interact with chlorothiazide/methyldopa
Note: Showing generic names only.
- acarbose
- acebutolol
- acetohexamide
- acrivastine
- albiglutide
- albuterol
- aldesleukin
- alfentanil
- alfuzosin
- allopurinol
- alogliptin
- alprazolam
- amantadine
- amifostine
- aminolevulinic acid
- aminolevulinic acid topical
- amiodarone
- amisulpride
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amphotericin b
- amphotericin b cholesteryl sulfate
- amphotericin b lipid complex
- amphotericin b liposomal
- anisindione
- apomorphine
- apraclonidine ophthalmic
- arformoterol
- aripiprazole
- arsenic trioxide
- asenapine
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- atenolol
- atracurium
- atropine
- avanafil
- baclofen
- bedaquiline
- belladonna
- benazepril
- benztropine
- betamethasone
- betaxolol
- betaxolol ophthalmic
- betiatide
- bexagliflozin
- biperiden
- bisacodyl
- bisoprolol
- bitolterol
- black cohosh
- brentuximab
- brexanolone
- brexpiprazole
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromfenac
- budesonide
- bumetanide
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
- cabergoline
- calaspargase pegol
- calcifediol
- calcipotriene topical
- calcitriol
- calcitriol topical
- calcium acetate
- calcium carbonate
- calcium chloride
- calcium citrate
- calcium glubionate
- calcium gluceptate
- calcium gluconate
- calcium glycerophosphate
- calcium lactate
- calcium phosphate, tribasic
- calcium saccharate
- canagliflozin
- cannabidiol
- cannabis
- capecitabine
- captopril
- carbamazepine
- carbonyl iron
- cariprazine
- carisoprodol
- carteolol
- carteolol ophthalmic
- carvedilol
- casanthranol
- cascara sagrada
- castor oil
- celecoxib
- cenobamate
- chlophedianol
- chloral hydrate
- chlordiazepoxide
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorpropamide
- chlorzoxazone
- cholecalciferol
- cholestyramine
- cisapride
- cisatracurium
- citalopram
- clidinium
- clobazam
- clofarabine
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clozapine
- codeine
- colestipol
- corticorelin
- corticotropin
- cortisone
- cosyntropin
- cyclophosphamide
- cyclosporine
- daclizumab
- dapagliflozin
- daridorexant
- darifenacin
- deflazacort
- demeclocycline
- deserpidine
- desipramine
- desmopressin
- desvenlafaxine
- dexamethasone
- dexlansoprazole
- dexmedetomidine
- dexmethylphenidate
- dextromethorphan
- diatrizoate
- diazepam
- diazoxide
- diclofenac
- dicumarol
- dicyclomine
- difelikefalin
- diflunisal
- dihydrotachysterol
- dimenhydrinate
- dimethyl fumarate
- diphenhydramine
- diroximel fumarate
- disopyramide
- divalproex sodium
- dobutamine
- dofetilide
- dolasetron
- dopamine
- doxacurium
- doxazosin
- doxepin
- doxepin topical
- doxercalciferol
- doxycycline
- doxylamine
- dronabinol
- dronedarone
- droperidol
- dulaglutide
- duloxetine
- efavirenz
- empagliflozin
- enalapril
- enalaprilat
- entacapone
- ephedrine
- ephedrine nasal
- epinephrine
- epirubicin
- epoprostenol
- eravacycline
- ergocalciferol
- ertugliflozin
- escitalopram
- eslicarbazepine
- esmolol
- esomeprazole
- ethacrynic acid
- ethanol
- etodolac
- etranacogene dezaparvovec
- etrasimod
- exenatide
- fenfluramine
- fenoldopam
- fenoprofen
- fentanyl
- ferric citrate
- ferric maltol
- ferrous fumarate
- ferrous gluconate
- ferrous sulfate
- fidanacogene elaparvovec
- finerenone
- flavoxate
- fludrocortisone
- fluorouracil
- fluoxetine
- fluphenazine
- flurazepam
- flurbiprofen
- fluvoxamine
- formoterol
- fosinopril
- furazolidone
- furosemide
- gabapentin
- gabapentin enacarbil
- ganaxolone
- garlic
- gepirone
- ginkgo
- glimepiride
- glipizide
- glyburide
- glycerin
- glycopyrrolate
- guanabenz
- guanadrel
- guanethidine
- guanfacine
- halazepam
- haloperidol
- heme iron polypeptide
- heroin
- house dust mite allergen extract
- hydralazine
- hydrocodone
- hydrocortisone
- hydromorphone
- hydroxyzine
- hyoscyamine
- ibuprofen
- idelalisib
- iloperidone
- iloprost
- imipramine
- indacaterol
- indomethacin
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- interferon beta-1a
- interferon beta-1b
- iodamide
- iodipamide
- iodixanol
- iohexol
- iomeprol
- iopamidol
- iopromide
- iothalamate
- ioversol
- ioxaglate
- ioxilan
- irinotecan
- irinotecan liposomal
- iron bisglycinate
- iron polysaccharide
- iron protein succinylate
- isocarboxazid
- isoetharine
- isoniazid
- labetalol
- lactitol
- lactulose
- lansoprazole
- lasmiditan
- leflunomide
- lemborexant
- levalbuterol
- levamlodipine
- levobetaxolol ophthalmic
- levobunolol ophthalmic
- levodopa
- levoketoconazole
- levomethadyl acetate
- levomilnacipran
- licorice
- lidocaine
- linagliptin
- linezolid
- liraglutide
- lisinopril
- lithium
- lixisenatide
- lofexidine
- lomitapide
- lorazepam
- loxapine
- lumateperone
- lurasidone
- ma huang
- magnesium citrate
- magnesium hydroxide
- maprotiline
- maraviroc
- meclofenamate
- mefenamic acid
- melatonin
- meloxicam
- mepenzolate
- meperidine
- mephentermine
- mephobarbital
- meprobamate
- mesoridazine
- metaproterenol
- metaraminol
- metformin
- methadone
- methdilazine
- methenamine
- methocarbamol
- methohexital
- methotrexate
- methotrimeprazine
- methoxamine
- methoxsalen
- methscopolamine
- methyl aminolevulinate topical
- methylene blue
- methylphenidate
- methylprednisolone
- metipranolol ophthalmic
- metocurine
- metoprolol
- metrizamide
- midazolam
- midodrine
- miglitol
- milnacipran
- mineral oil
- minocycline
- mipomersen
- mirtazapine
- mitotane
- mivacurium
- mixed grass pollens allergen extract
- moexipril
- molindone
- monomethyl fumarate
- morphine
- morphine liposomal
- multivitamin with iron
- multivitamin with iron and fluoride
- multivitamin with minerals
- multivitamin, prenatal
- nabilone
- nabumetone
- nadolol
- nalbuphine
- naltrexone
- naproxen
- nateglinide
- nebivolol
- nefazodone
- norepinephrine
- nortriptyline
- olanzapine
- oliceridine
- olodaterol
- olopatadine nasal
- omadacycline
- omeprazole
- opicapone
- opium
- orphenadrine
- oxaprozin
- oxazepam
- oxybutynin
- oxycodone
- oxytetracycline
- ozanimod
- paliperidone
- palopegteriparatide
- pancuronium
- pantoprazole
- paraldehyde
- paricalcitol
- paroxetine
- peanut allergen powder
- pegaspargase
- peginterferon beta-1a
- penbutolol
- pentazocine
- pentobarbital
- pentoxifylline
- perindopril
- perphenazine
- pexidartinib
- phenelzine
- phenobarbital
- phenolphthalein
- phenylbutazone
- phenylephrine
- phenylpropanolamine
- pimozide
- pindolol
- pioglitazone
- pipecuronium
- pirbuterol
- piroxicam
- polyethylene glycol 3350
- polyethylene glycol 3350 with electrolytes
- porfimer
- pramlintide
- prazosin
- prednisolone
- prednisone
- primidone
- procarbazine
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propantheline
- propiomazine
- propoxyphene
- propranolol
- protriptyline
- pseudoephedrine
- pyrilamine
- pyrophosphate
- rabeprazole
- ragweed pollen allergen extract
- ramipril
- rapacuronium
- rasagiline
- rauwolfia serpentina
- remdesivir
- remifentanil
- remimazolam
- repaglinide
- reserpine
- rifampin
- riociguat
- risperidone
- ritodrine
- rocuronium
- rofecoxib
- rosiglitazone
- rufinamide
- safinamide
- salmeterol
- saxagliptin
- scopolamine
- secobarbital
- selegiline
- selexipag
- semaglutide
- senna
- sertraline
- sibutramine
- sildenafil
- sitagliptin
- sodium nitrite
- sodium oxybate
- solifenacin
- sotagliflozin
- sotalol
- sparsentan
- succinylcholine
- sufentanil
- sulindac
- tadalafil
- taurine
- temazepam
- terazosin
- terbutaline
- teriflunomide
- tetrabenazine
- tetracycline
- thiethylperazine
- thioguanine
- thiopental
- thioridazine
- thiothixene
- tigecycline
- timolol
- timolol ophthalmic
- timothy grass pollen allergen extract
- tirzepatide
- tizanidine
- tofacitinib
- tolazamide
- tolbutamide
- tolcapone
- tolmetin
- tolterodine
- topiramate
- toremifene
- torsemide
- trabectedin
- tramadol
- trandolapril
- tranylcypromine
- trazodone
- treprostinil
- triamcinolone
- triazolam
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimipramine
- triprolidine
- troglitazone
- trospium
- tubocurarine
- valdecoxib
- valerian
- valoctocogene roxaparvovec
- valproic acid
- vamorolone
- vardenafil
- vasopressin
- vecuronium
- venlafaxine
- vericiguat
- verteporfin
- vilazodone
- vortioxetine
- vosoritide
Chlorothiazide/methyldopa alcohol/food interactions
There are 3 alcohol/food interactions with chlorothiazide / methyldopa.
Chlorothiazide/methyldopa disease interactions
There are 19 disease interactions with chlorothiazide / methyldopa which include:
- liver disease
- anuria
- electrolyte losses
- liver disease
- lupus erythematosus
- renal function disorders
- cerebrovascular disease
- dialysis
- hemolytic anemia
- leukopenia
- peripheral edema
- pheochromocytoma
- asthma
- diabetes
- hyperlipidemia
- hyperparathyroidism
- hyperuricemia
- thyroid function tests
- psychoses
More about chlorothiazide / methyldopa
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: antiadrenergic agents (central) with thiazides
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.