Drug Interactions between buspirone and Symproic
This report displays the potential drug interactions for the following 2 drugs:
- buspirone
- Symproic (naldemedine)
Interactions between your drugs
No interactions were found between buspirone and Symproic. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
buspirone
A total of 502 drugs are known to interact with buspirone.
- Buspirone is in the drug class miscellaneous anxiolytics, sedatives and hypnotics.
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Buspirone is used to treat the following conditions:
- Anxiety
- Borderline Personality Disorder (off-label)
- Panic Disorder
- Sexual Dysfunction, SSRI Induced (off-label)
Symproic
A total of 168 drugs are known to interact with Symproic.
- Symproic is in the drug class peripheral opioid receptor antagonists.
- Symproic is used to treat Opioid-Induced Constipation.
Drug and food interactions
busPIRone food
Applies to: buspirone
You should avoid the use of alcohol while being treated with busPIRone. Alcohol can increase the nervous system side effects of busPIRone such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Patients receiving busPIRone should preferably avoid the consumption of large amounts of grapefruits and grapefruit juice. If this is not possible, the busPIRone dose should be taken at least 2 hours before or 8 hours after grapefruit or grapefruit juice. Large amounts of grapefruit and grapefruit juice may cause increased levels of busPIRone in your body. This can lead to increased adverse effects such as drowsiness. Talk to your doctor or pharmacist if you have any questions or concerns.
naldemedine food
Applies to: Symproic (naldemedine)
Grapefruit juice can increase the blood levels of naldemedine. This may increase side effects and withdrawal symptoms such as sweating, tearing, runny nose, chills, diarrhea, abdominal pain, anxiety, insomnia, irritability, restlessness, and yawning. You should limit the consumption of grapefruit and grapefruit juice during treatment with naldemedine. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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