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Drug Interactions between amoxicillin / clarithromycin / lansoprazole and fluconazole

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

fluconazole lansoprazole

Applies to: fluconazole and amoxicillin / clarithromycin / lansoprazole

Fluconazole can increase the blood levels of lansoprazole. This may increase side effects such as diarrhea, abdominal pain, nausea, vomiting, and flatulence. During long-term treatment, you may also have an increased risk of developing osteoporosis, bone fractures, and a condition called hypomagnesemia (low blood magnesium), which in severe cases can lead to muscle spasm, irregular heart rhythm, and seizures. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

clarithromycin lansoprazole

Applies to: amoxicillin / clarithromycin / lansoprazole and amoxicillin / clarithromycin / lansoprazole

Clarithromycin may increase the blood levels and side effects of lansoprazole in some people. Contact your doctor if you experience diarrhea or other intestinal problems. You may need a dose adjustment if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

fluconazole clarithromycin

Applies to: fluconazole and amoxicillin / clarithromycin / lansoprazole

Information for this minor interaction is available on the professional version.

Minor

amoxicillin clarithromycin

Applies to: amoxicillin / clarithromycin / lansoprazole and amoxicillin / clarithromycin / lansoprazole

Information for this minor interaction is available on the professional version.

Drug and food interactions

Minor

clarithromycin food

Applies to: amoxicillin / clarithromycin / lansoprazole

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer