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Drug Interactions between amiloride and doxycycline

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

doxycycline aMILoride

Applies to: doxycycline and amiloride

Using doxycycline together with aMILoride may result in reduced kidney function as well as changes in your electrolyte levels. The risk of this adverse reaction may be increased or decreased depending on the specific water pill and antibiotic combination as well as on your overall health status. Your doctor may already be aware of the interaction but has determined that this is the best course of treatment for you and is monitoring you closely for any potential complications. Contact your doctor immediately if you notice any signs or symptoms of kidney damage such as urinating less often, shortness of breath, fatigue, confusion, nausea, weakness, irregular heartbeat, chest pain or pressure, and/or swelling in your legs, ankles, or feet. Let your doctor know if you experience any side effects that are particularly bothersome. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

aMILoride food

Applies to: amiloride

AMILoride and ethanol (alcohol) may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

doxycycline food

Applies to: doxycycline

Iron can bind to doxycycline in the gastrointestinal tract, which may prevent their absorption into the bloodstream and possibly reduce their effectiveness. To avoid or minimize the interaction, iron-containing medications and doxycycline should preferably be taken at least three to four hours apart in most cases. Talk to your doctor if you have any questions or concerns, or if you have trouble separating the dosing times. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

doxycycline food

Applies to: doxycycline

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer