Xanax XR Interactions
There are 560 drugs known to interact with Xanax XR (alprazolam), along with 9 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 55 are major, 465 are moderate, and 40 are minor.
- View all 560 medications that may interact with Xanax XR
- View Xanax XR alcohol/food interactions (2)
- View Xanax XR disease interactions (9)
Most frequently checked interactions
View interaction reports for Xanax XR (alprazolam) and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- clonazepam
- Cymbalta (duloxetine)
- Effexor XR (venlafaxine)
- gabapentin
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- levothyroxine
- Lexapro (escitalopram)
- lisinopril
- Lyrica (pregabalin)
- melatonin
- metformin
- omeprazole
- propranolol
- Prozac (fluoxetine)
- Seroquel (quetiapine)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Topamax (topiramate)
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Wellbutrin XL (bupropion)
- Zoloft (sertraline)
Xanax XR alcohol/food interactions
There are 2 alcohol/food interactions with Xanax XR (alprazolam).
Xanax XR disease interactions
There are 9 disease interactions with Xanax XR (alprazolam) which include:
- acute alcohol intoxication
- closed-angle glaucoma
- drug dependence
- renal/liver disease
- respiratory depression
- seizures
- depression
- obesity
- paradoxical reactions
Report options
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More about Xanax XR (alprazolam)
- Xanax XR consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (82)
- Drug images
- Latest FDA alerts (3)
- Side effects
- Dosage information
- During pregnancy
- Generic availability
- Support group
- Drug class: benzodiazepines
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
