Drug Interactions between allopurinol and Hecoria
This report displays the potential drug interactions for the following 2 drugs:
- allopurinol
- Hecoria (tacrolimus)
Interactions between your drugs
No interactions were found between allopurinol and Hecoria. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
allopurinol
A total of 431 drugs are known to interact with allopurinol.
- Allopurinol is in the following drug classes: antigout agents, antihyperuricemic agents.
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Allopurinol is used to treat the following conditions:
- Calcium Oxalate Calculi with Hyperuricosuria
- Cardiothoracic Surgery (off-label)
- Gout
- High Risk Percutaneous Transluminal Angioplasty (off-label)
- Hyperuricemia Secondary to Chemotherapy
- Leishmaniasis (off-label)
- Mania (off-label)
- Reactive Perforating Collangenosis (off-label)
- Urinary Tract Stones (off-label)
Hecoria
A total of 837 drugs are known to interact with Hecoria.
- Hecoria is in the drug class calcineurin inhibitors.
- Hecoria is used to treat the following conditions:
Drug and food interactions
allopurinol food
Applies to: allopurinol
Consumer information for this interaction is not currently available.
ADJUST DOSING INTERVAL: The tolerability of allopurinol may be improved by giving it after a meal. Additionally, when the dose is greater than 300 mg, dividing the total daily dose into smaller doses administered more often may be appropriate to help minimize gastrointestinal irritation.
MONITOR: Concomitant use of allopurinol with central nervous system (CNS) depressants, including alcohol, may potentiate adverse effects such as somnolence and sedation.
MANAGEMENT: To improve tolerability, some manufacturers suggest administering allopurinol after a meal. Additionally, if the daily dose is greater than 300 mg, administering allopurinol in divided doses may help reduce gastrointestinal intolerance. Patients should also be counseled to avoid or limit consumption of alcohol and to avoid activities requiring mental alertness such as driving or operating hazardous machinery until they know how the medication affects them.
tacrolimus food
Applies to: Hecoria (tacrolimus)
Tacrolimus should be taken on a consistent schedule before or after you eat at the same times each day. Grapefruit and grapefruit juice may increase the amount of tacrolimus in your body. This can lead to potentially dangerous side effects and should be avoided. If you are already consuming grapefruit products, do not increase or decrease the amount of these products in your diet without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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