Acetaminophen/phenylephrine Interactions
There are 310 drugs known to interact with acetaminophen/phenylephrine, along with 7 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 34 are major, 255 are moderate, and 21 are minor.
- View all 310 medications that may interact with acetaminophen/phenylephrine
- View acetaminophen/phenylephrine alcohol/food interactions (2)
- View acetaminophen/phenylephrine disease interactions (7)
Most frequently checked interactions
View interaction reports for acetaminophen / phenylephrine and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- Advair Diskus (fluticasone / salmeterol)
- Advil (ibuprofen)
- Advil Cold and Sinus (ibuprofen / pseudoephedrine)
- Advil Dual Action (acetaminophen / ibuprofen)
- Alcohol (contained in alcoholic beverages) (ethanol)
- Aleve (naproxen)
- Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate)
- Allegra (fexofenadine)
- Allegra Allergy (fexofenadine)
- Alupent (metaproterenol)
- Ambien CR (zolpidem)
- Anoro Ellipta (umeclidinium / vilanterol)
- Artificial Tears (ocular lubricant ophthalmic)
- Aspercreme (trolamine salicylate topical)
- Aspirin Low Strength (aspirin)
- Augmentin (amoxicillin / clavulanate)
- Azstarys (dexmethylphenidate / serdexmethylphenidate)
- Benadryl (diphenhydramine)
- Effexor XR (venlafaxine)
- Flax Seed Oil (flax)
- Prevacid (lansoprazole)
- Provigil (modafinil)
- Sudafed PE Congestion (phenylephrine)
- Trintellix (vortioxetine)
- Vitamin C with Rose Hips (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vitamin K2 (menaquinone)
- Zantac (ranitidine)
Acetaminophen/phenylephrine alcohol/food interactions
There are 2 alcohol/food interactions with acetaminophen / phenylephrine.
Acetaminophen/phenylephrine disease interactions
There are 7 disease interactions with acetaminophen / phenylephrine which include:
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More about acetaminophen / phenylephrine
- acetaminophen/phenylephrine consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (8)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
