Percocet Interactions
There are 687 drugs known to interact with Percocet (acetaminophen/oxycodone), along with 19 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 220 are major, 454 are moderate, and 13 are minor.
- View all 687 medications that may interact with Percocet
- View Percocet alcohol/food interactions (1)
- View Percocet disease interactions (19)
Most frequently checked interactions
View interaction reports for Percocet (acetaminophen / oxycodone) and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- albuterol
- Ambien (zolpidem)
- amlodipine
- aspirin
- atorvastatin
- baclofen
- clonazepam
- cyclobenzaprine
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- gabapentin
- ibuprofen
- levothyroxine
- lisinopril
- Lyrica (pregabalin)
- metformin
- metoprolol
- omeprazole
- oxycodone
- pantoprazole
- prednisone
- tizanidine
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zofran (ondansetron)
Percocet alcohol/food interactions
There is 1 alcohol/food interaction with Percocet (acetaminophen / oxycodone).
Percocet disease interactions
There are 19 disease interactions with Percocet (acetaminophen / oxycodone) which include:
- alcoholism
- liver disease
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- PKU
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
Report options
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More about Percocet (acetaminophen / oxycodone)
- Percocet consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (234)
- Drug images
- Latest FDA alerts (6)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: narcotic analgesic combinations
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
