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Alka-Seltzer Plus Cold Interactions

There are 600 drugs known to interact with Alka-Seltzer Plus Cold (acetaminophen/chlorpheniramine/phenylephrine), along with 11 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 46 are major, 539 are moderate, and 15 are minor.

Does Alka-Seltzer Plus Cold interact with my other drugs?

Enter medications to view a detailed interaction report using our Drug Interaction Checker.

Most frequently checked interactions

View interaction reports for Alka-Seltzer Plus Cold (acetaminophen / chlorpheniramine / phenylephrine) and the medicines listed below.

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Alka-Seltzer Plus Cold alcohol/food interactions

There is 1 alcohol/food interaction with Alka-Seltzer Plus Cold (acetaminophen / chlorpheniramine / phenylephrine).

Alka-Seltzer Plus Cold disease interactions

There are 11 disease interactions with Alka-Seltzer Plus Cold (acetaminophen / chlorpheniramine / phenylephrine) which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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