Combiflex Interactions
There are 645 drugs known to interact with Combiflex (acetaminophen / caffeine / phenyltoloxamine / salicylamide), along with 22 disease interactions, and 5 alcohol/food interactions. Of the total drug interactions, 29 are major, 592 are moderate, and 24 are minor.
- View all 645 medications that may interact with Combiflex
- View Combiflex alcohol/food interactions (5)
- View Combiflex disease interactions (22)
Most frequently checked interactions
View interaction reports for Combiflex (acetaminophen / caffeine / phenyltoloxamine / salicylamide) and the medicines listed below.
- calcium carbonate
- cefixime
- cholestyramine
- clindamycin
- De Omega Benefits (cholecalciferol / omega-3 polyunsaturated fatty acids)
- Estrace Vaginal Cream (estradiol topical)
- meclizine
- metronidazole topical
- multivitamin with minerals
- ofloxacin
- Paracetamol (acetaminophen)
- polyethylene glycol 3350
- PreserVision AREDS 2 (multivitamin with minerals)
- Prolia (denosumab)
- Refresh Optive Mega-3 (ocular lubricant ophthalmic)
- Refresh Tears (ocular lubricant ophthalmic)
- Restasis (cyclosporine ophthalmic)
- Synthroid (levothyroxine)
- Viibryd (vilazodone)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Wixela Inhub (fluticasone / salmeterol)
Combiflex alcohol/food interactions
There are 5 alcohol/food interactions with Combiflex (acetaminophen / caffeine / phenyltoloxamine / salicylamide).
Combiflex disease interactions
There are 22 disease interactions with Combiflex (acetaminophen / caffeine / phenyltoloxamine / salicylamide) which include:
- alcoholism
- liver disease
- cardiac disease
- hypertension
- psychiatric disorders
- PUD
- GI toxicity
- Reye's syndrome
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- cardiotoxicity
- liver disease
- renal dysfunction
- seizure disorders
- GERD
- anemia
- coagulation
- G-6-PD deficiency
- hepatotoxicity
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.