Excedrin PM Headache Interactions
There are 765 drugs known to interact with Excedrin PM Headache (acetaminophen / aspirin / diphenhydramine), along with 20 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 72 are major, 667 are moderate, and 26 are minor.
- View all 765 medications that may interact with Excedrin PM Headache
- View Excedrin PM Headache alcohol/food interactions (2)
- View Excedrin PM Headache disease interactions (20)
Most frequently checked interactions
View interaction reports for Excedrin PM Headache (acetaminophen / aspirin / diphenhydramine) and the medicines listed below.
- acetaminophen
- amlodipine
- Benadryl (diphenhydramine)
- biotin
- buspirone
- cetirizine
- cyclobenzaprine
- diazepam
- doxycycline
- Excedrin (acetaminophen / aspirin / caffeine)
- Excedrin Migraine (acetaminophen / aspirin / caffeine)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- fluconazole
- fluoxetine
- folic acid
- gabapentin
- ibuprofen
- levothyroxine
- losartan
- magnesium citrate
- magnesium oxide
- melatonin
- meloxicam
- metformin
- omeprazole
- prednisone
- rosuvastatin
- sumatriptan
- Vitamin D3 (cholecalciferol)
Excedrin PM Headache alcohol/food interactions
There are 2 alcohol/food interactions with Excedrin PM Headache (acetaminophen / aspirin / diphenhydramine).
Excedrin PM Headache disease interactions
There are 20 disease interactions with Excedrin PM Headache (acetaminophen / aspirin / diphenhydramine) which include:
- alcoholism
- liver disease
- depression
- coagulation
- asthma
- GI toxicity
- renal dysfunction
- Reye's syndrome
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- anemia
- dialysis
- G-6-PD deficiency
- hepatotoxicity
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.