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Drug Interactions between Abraxane and COVID-19 mRNA (Pfizer) vaccine

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

PACLitaxel protein-bound SARS-CoV-2 (COVID-19) mRNA-LNP vaccine (cvx 309)

Applies to: Abraxane (paclitaxel protein-bound) and COVID-19 mRNA (Pfizer) vaccine

If you are currently being treated or have recently been treated with PACLitaxel protein-bound, you should let your doctor know before receiving SARS-CoV-2 (COVID-19) mRNA-LNP vaccine (cvx 309). Depending on the dose and length of time you have been on PACLitaxel protein-bound, you may have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of PACLitaxel protein-bound therapy. If you have recently been vaccinated with SARS-CoV-2 (COVID-19) mRNA-LNP vaccine (cvx 309), your doctor may choose to postpone treatment with PACLitaxel protein-bound for a couple of weeks or more. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

PACLitaxel protein-bound food

Applies to: Abraxane (paclitaxel protein-bound)

Grapefruits and grapefruit juice may increase the blood levels and effects of PACLitaxel protein-bound. This can increase the risk of side effects such as nausea, diarrhea, hair loss, muscle pain or weakness, nerve damage, and impaired bone marrow function resulting in low numbers of different types of blood cells. You may also be more likely to develop anemia, bleeding problems, or infections due to low blood cell counts. Contact your doctor if you experience paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, pain or burning during urination, vision problems, and/or numbness, burning or tingling in your hands and feet. You may need a dose adjustment and/or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer