Sulfonylureas
What are Sulfonylureas?
Sulfonylureas are a group of medicines used in the management of Type 2 diabetes. Sulfonylureas lower blood glucose levels by stimulating insulin release from the Beta cells of the pancreas. Their action is dependent upon the presence of functioning Beta cells, therefore, sulfonylureas do not work in people with type 1 diabetes.
Sulfonylureas stimulate insulin release by blocking ATP sensitive potassium channels in the Beta cells, reducing potassium permeability. This causes depolarization of the cell and increases calcium entry, increasing insulin secretion.
List of Sulfonylureas
View by Generic | Brand
| Drug Name | Avg. Rating | Reviews |
|---|---|---|
| glipizide systemic (Pro) Brand names: Glucotrol XL, Glucotrol, GlipiZIDE XL |
76 reviews | |
| glimepiride systemic (Pro) Brand name: Amaryl |
71 reviews | |
| glyburide systemic (Pro) Brand names: Glycron, Glynase, DiaBeta, Glynase PresTab |
9 reviews | |
| For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective). | ||
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.