Triferic Avnu Dosage

2.2 Preparation and Administration

Each ampule of Triferic AVNU is intended for single-use only.

Use aseptic technique to prepare Triferic AVNU as follows:

• Visually inspect Triferic AVNU solution for signs of precipitation prior to use. The solution should be clear and slightly yellow-green in color.
• Holding the top of the ampule, shake with one single downward movement in order to remove the solution remaining in the cap.
• To open, twist the ampule body and the ampule head in opposite directions until the neck breaks off the top.
• Attach a 10 mL or 20 mL luer-lock syringe to the ampule and withdraw the contents (6.75 mg in 4.5 mL).
• Connect the syringe to the attached pre-dialyzer infusion line, post-dialyzer infusion line, or to a separate connection to the venous blood line.
• Mount the syringe on an infusion pump and administer as a slow continuous infusion of Triferic AVNU (4.5 mL) over 3 to 4 hours.
• Discard unused portion.