Seizalam Injection Dosage

Recommended Dose

The recommended dose of SEIZALAM is 10 mg, administered by intramuscular injection.

Important Administration Instructions

SEIZALAM should be administered by a healthcare professional who has had adequate training in the recognition and treatment of status epilepticus.

SEIZALAM is for intramuscular use only. Inject in the mid-outer thigh (vastus lateralis muscle).

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.

Monitoring

After administration of SEIZALAM, continuous monitoring of respiratory and cardiac function is recommended until the patient is stabilized. Serious and life-threatening cardiorespiratory adverse reactions, such as hypoventilation, airway obstruction, apnea, and hypotension have been reported with the use of midazolam. Patients should be monitored in a setting that allows for immediate access to resuscitative drugs. Appropriate resuscitation equipment and personnel trained in their use and skilled in airway management should be available.

Observation for signs of cardiorespiratory depression is particularly important in patients with chronic obstructive pulmonary disease (COPD), patients 60 or more years of age, and patients who have received concomitant narcotics or other central nervous system (CNS) depressants.