Promethazine DM Dosage

Generic name: DEXTROMETHORPHAN HYDROBROMIDE 15mg in 5mL, PROMETHAZINE HYDROCHLORIDE 6.25mg in 5mL
Dosage form: oral solution
Drug class: Upper respiratory combinations

Medically reviewed by Drugs.com. Last updated on Feb 3, 2025.

Promethazine hydrochloride and dextromethorphan hydrobromide oral solution is contraindicated for children under 2 years of age (see WARNINGS – Black Box Warning and Use In Pediatric Patients).

The average effective dose is given in the following table:

Adults	1 teaspoonful (5 mL) every 4 to 6 hours, not to exceed 30 mL in 24 hours.
Children 6 Years To Under 12 Years	½ to 1 teaspoonful (2.5 to 5 mL) every 4 to 6 hours, not to exceed 20 mL in 24 hours.
Children 2 Years To Under 6 Years	¼ to ½ teaspoonful (1.25 to 2.5 mL) every 4 to 6 hours, not to exceed 10 mL in 24 hours.