Mineral Oil Dosage
Medically reviewed by Drugs.com. Last updated on Oct 4, 2024.
Applies to the following strengths: 100%; 28%
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Constipation - Acute
Oral:
Heavy liquid: 30 to 60 mL orally once a day at bedtime
Non-emulsified liquid: 30 to 45 mL orally
Suspension/microemulsion: 30 to 90 mL orally once a day (or as directed)
- Maximum dose: 90 mL/day
Rectal: 118 mL rectally once a day
Comments:
- Non-emulsified liquid formulations should be taken at least 2 hours prior to/after other oral drugs.
- Suspension/microemulsion formulations may be taken as a single dose or given in up to 3 equally divided doses.
Uses:
- Relief of fecal impaction
- Relief of occasional constipation
- Removal of residue after barium administration
Usual Adult Dose for Constipation
Oral:
Heavy liquid: 30 to 60 mL orally once a day at bedtime
Non-emulsified liquid: 30 to 45 mL orally
Suspension/microemulsion: 30 to 90 mL orally once a day (or as directed)
- Maximum dose: 90 mL/day
Rectal: 118 mL rectally once a day
Comments:
- Non-emulsified liquid formulations should be taken at least 2 hours prior to/after other oral drugs.
- Suspension/microemulsion formulations may be taken as a single dose or given in up to 3 equally divided doses.
Uses:
- Relief of fecal impaction
- Relief of occasional constipation
- Removal of residue after barium administration
Usual Adult Dose for Fecal Impaction
Oral:
Heavy liquid: 30 to 60 mL orally once a day at bedtime
Non-emulsified liquid: 30 to 45 mL orally
Suspension/microemulsion: 30 to 90 mL orally once a day (or as directed)
- Maximum dose: 90 mL/day
Rectal: 118 mL rectally once a day
Comments:
- Non-emulsified liquid formulations should be taken at least 2 hours prior to/after other oral drugs.
- Suspension/microemulsion formulations may be taken as a single dose or given in up to 3 equally divided doses.
Uses:
- Relief of fecal impaction
- Relief of occasional constipation
- Removal of residue after barium administration
Usual Pediatric Dose for Constipation - Acute
Rectal:
- Children 2 to 12 years: 59 mL rectally once a day
- Children 12 years and older: 118 mL rectally once a day
Oral:
Heavy liquid:
Children 6 to 12 years: 5 to 15 mL orally once a day (at bedtime)
Children 12 years and older: 15 to 30 mL orally once a day (at bedtime)
Non-emulsified liquid:
Children 6 to 12 years: 5 to 15 mL orally once a day (at bedtime)
- Maximum dose: 15 mL/24 hours
- Maximum dose: 45 mg/24 hours
Suspension/microemulsion:
Children 6 to 12 years: 10 to 30 mL orally once a day (or as directed)
Children 12 years and older: 30 to 90 mL orally once a day (or as directed)
- Maximum dose: 90 mL/day
Comments:
- Non-emulsified liquid formulations should be taken at least 2 hours prior to/after other oral drugs.
- Suspension/microemulsion formulations may be taken as a single dose or given in up to 3 equally divided doses.
Uses:
- Relief of fecal impaction
- Relief of occasional constipation
- Removal of residue after barium administration
Usual Pediatric Dose for Constipation
Rectal:
- Children 2 to 12 years: 59 mL rectally once a day
- Children 12 years and older: 118 mL rectally once a day
Oral:
Heavy liquid:
Children 6 to 12 years: 5 to 15 mL orally once a day (at bedtime)
Children 12 years and older: 15 to 30 mL orally once a day (at bedtime)
Non-emulsified liquid:
Children 6 to 12 years: 5 to 15 mL orally once a day (at bedtime)
- Maximum dose: 15 mL/24 hours
- Maximum dose: 45 mg/24 hours
Suspension/microemulsion:
Children 6 to 12 years: 10 to 30 mL orally once a day (or as directed)
Children 12 years and older: 30 to 90 mL orally once a day (or as directed)
- Maximum dose: 90 mL/day
Comments:
- Non-emulsified liquid formulations should be taken at least 2 hours prior to/after other oral drugs.
- Suspension/microemulsion formulations may be taken as a single dose or given in up to 3 equally divided doses.
Uses:
- Relief of fecal impaction
- Relief of occasional constipation
- Removal of residue after barium administration
Usual Pediatric Dose for Fecal Impaction
Rectal:
- Children 2 to 12 years: 59 mL rectally once a day
- Children 12 years and older: 118 mL rectally once a day
Oral:
Heavy liquid:
Children 6 to 12 years: 5 to 15 mL orally once a day (at bedtime)
Children 12 years and older: 15 to 30 mL orally once a day (at bedtime)
Non-emulsified liquid:
Children 6 to 12 years: 5 to 15 mL orally once a day (at bedtime)
- Maximum dose: 15 mL/24 hours
- Maximum dose: 45 mg/24 hours
Suspension/microemulsion:
Children 6 to 12 years: 10 to 30 mL orally once a day (or as directed)
Children 12 years and older: 30 to 90 mL orally once a day (or as directed)
- Maximum dose: 90 mL/day
Comments:
- Non-emulsified liquid formulations should be taken at least 2 hours prior to/after other oral drugs.
- Suspension/microemulsion formulations may be taken as a single dose or given in up to 3 equally divided doses.
Uses:
- Relief of fecal impaction
- Relief of occasional constipation
- Removal of residue after barium administration
Renal Dose Adjustments
Rectal: Data not available
Oral:
Heavy liquid:
- Renal dysfunction: Data not available
- Renal failure: Contraindicated
Non-emulsified liquid, suspension/microemulsion: Data not available
Liver Dose Adjustments
Data not available
Precautions
CONTRAINDICATIONS:
Rectal:
- Patients with abdominal pain, nausea, or vomiting (unless otherwise directed)
Oral:
Heavy liquid:
- Infants or young children (unless otherwise directed)
- Older patients (unless otherwise directed)
- Patients who are bedridden (unless otherwise directed)
- Patients with abdominal pain, bowel habit changes lasting longer than 2 weeks, nausea, vomiting, rectal bleeding, and/or renal failure
- Use for longer than 1 week
Non-emulsified liquid:
- Children under 6 years of age
- Older patients
- Patients who are bedridden
- Patients with difficulty swallowing
- Pregnant patients
- Use for longer than 1 week
Suspension/microemulsion:
- Children under 6 years of age
- Patients who are bedridden
- Patients with difficulty swallowing
- Pregnant patients
Safety and efficacy of rectal formulations have not been established in patients younger than 2 years; this drug is not recommended for use in these patients.
Safety and efficacy of some oral formulations have not been established in patients younger than 6 years; this drug is not recommended for use in these patients.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- This drug should not be taken with meals.
- Oral liquid formulations should be mixed/shaken well prior to administration.
- Some experts recommend avoiding administration of oral formulations less than 2 hours before lying down.
Storage requirements:
- Oral: Protect from light; keep bottle tightly closed when not in use.
Monitoring:
- GASTROINTESTINAL: Sudden, persistent bowel function changes over 2 weeks; rectal bleeding or continued constipation during treatment
Patient advice:
- Advise patients to speak to their healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding.
- Patients should be instructed to stop treatment and seek further advice if rectal bleeding occurs and/or they fail to have a bowel movement.
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