Lampit Dosage

Generic name: NIFURTIMOX 30mg
Dosage form: tablet, film coated
Drug class: Miscellaneous antibiotics

Medically reviewed by Drugs.com. Last updated on Jun 2, 2023.

•: LAMPIT (30 mg and 120 mg) tablets are for oral use and must be taken with food.
•: LAMPIT tablets are dosed by body weight of the patient.
•: LAMPIT (30 mg and 120 mg) tablets are functionally scored tablets which can be split into one-half (15 mg and 60 mg respectively) at the scored lines by hand. Do not break LAMPIT tablets mechanically with a tablet splitting device.
•: LAMPIT 30 mg and 120 mg tablets can be made into a slurry as an alternative method of administration for patients who cannot swallow the tablets.
•: Discontinue consumption of alcohol during treatment with LAMPIT.
•: Complete the full course of treatment to prevent recurrence of the infection.
•: If a dose is missed, take the missed dose as soon as possible together with food. However, if it is within 3 hours of the next scheduled dose, skip the missed dose and continue treatment as prescribed. Do not take a double dose to make up for a missed dose.

•: Administer LAMPIT (30 mg and 120 mg) tablets orally three times a day with food.
•: Total daily recommended dosages of LAMPIT are based on the body weight of the patient (see Table 1).
•: Adjust LAMPIT dosage accordingly if body weight decreases during treatment.
•: The recommended duration of treatment with LAMPIT is 60 days.

Table 1: Total Daily Recommended Dosages of LAMPIT Based on Body Weight

Age	Body weight group	Total daily dose of nifurtimox (mg/kg)
Birtha to less than 18 years	41 kg or greater	8 to 10
Birtha to less than 18 years	Less than 41 kg	10 to 20

aTerm newborn with body weight of greater than or equal to 2.5 kg

Table 2: Individual Dosages Based on Body Weight in Pediatric Patients (Birtha to Less than 18 years of age)

Body weight (kg)	Dose (mg)	Number of LAMPIT 30 mg tablets per dose (3 x Daily)	Number of LAMPIT 120 mg tablets per dose (3 x Daily)
2.5 kg to 4.5 kg	15 mg	½ tablet	—
4.6 kg to less than 9 kg	30 mg	1 tablet	—
9 kg to less than 13 kg	45 mg	1 ½ tablets	—
13 kg to less than 18 kg	60 mg	2 tablets	½ tablet
18 kg to less than 22 kg	75 mg	2 ½ tablets	—
22 kg to less than 27 kg	90 mg	3 tablets	—
27 kg to less than 35 kg	120 mg	4 tablets	1 tablet
35 kg to less than 41 kg	180 mg	—	1 ½ tablets
41 kg to less than 51 kg	120 mg	—	1 tablet
51 kg to less than 71 kg	180 mg	—	1 ½ tablets
71 kg to less than 91 kg	240 mg	—	2 tablets
91 kg or greater	300 mg	—	2 ½ tablets

aTerm newborn with body weight of greater than or equal to 2.5 kg

Obtain a pregnancy test in females of reproductive potential prior to initiating treatment with LAMPIT.

Do not break LAMPIT tablets mechanically with a tablet splitting device. A functional score line is used to divide the tablet by hand as follows:

•: To split LAMPIT tablet, place the tablet on a flat surface with the score line facing up.
•: With the tablet resting on the flat surface, apply enough downward pressure with the index finger centered on the top of the tablet to break it along the score line.