Hyaluronan Dosage
Medically reviewed by Drugs.com. Last updated on Nov 27, 2023.
Applies to the following strengths: 30 mg/2 mL; 88 mg/4 mL; 24 mg/3 mL
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Osteoarthritis
Inject the contents of one prefilled syringe intraarticularly into the knee once a week for 3 to 4 weeks
Use: For the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy and to simple analgesics (e.g., acetaminophen)
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
CONTRAINDICATIONS:
- Hypersensitivity to the active component or any of the ingredients
- Hypersensitivity to gram positive bacterial proteins
- Do not inject in the knees of patients with infections or skin diseases near the injection site or joint
Safety and efficacy have not been established in patients younger than 18 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- Strict aseptic injection technique should be used during the application of this drug.
- Remove joint effusion, if present, before injecting this drug.
- The prefilled syringe is for a single use only.
Storage requirements:
- Store in original package at room temperature (below 77F/25C).
- Do not freeze.
Patient advice:
- Transient pain or swelling may occur after the injection.
- Avoid strenuous activity or prolonged weight-bearing activities such as funning or tennis within 48 hours following the injection.
- Pain relief may not be seen until after the third injection.
Frequently asked questions
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