Fludrocortisone Dosage

Medically reviewed by Drugs.com. Last updated on Aug 10, 2023.

Usual Adult Dose for Addison's Disease

0.1 mg orally per day
Maintenance dose: 0.1 mg orally 3 times a week to 0.2 mg orally per day

Comments:

• If transient hypertension occurs as a consequence of therapy, dose should be reduced to 0.05 mg per day
• Often given concomitantly with cortisone or hydrocortisone.

Use: For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease

Usual Adult Dose for Adrenogenital Syndrome

0.1 to 0.2 mg orally per day

Use: For the treatment of salt-losing adrenogenital syndrome

Renal Dose Adjustments

Use with caution.

Liver Dose Adjustments

Use with caution.

Precautions

CONTRAINDICATIONS:

• Hypersensitivity to the active component or to any of the ingredients
• Systemic fungal infections

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Doses are dependent upon severity of the disease and response of individual patients.
• Continually monitor patients for signs that indicate dose adjustment may be necessary, including remission or exacerbations of disease and stress (surgery, infection, trauma).
• If a dose is missed, take it as soon as it is remembered unless it is almost time for the next dose; doses should not be doubled.

Storage requirements:

• Avoid excessive heat.
• Dispense in a tightly closed, light-resistant container.

Monitoring:

• Cardiovascular: Monitor blood pressure regularly.
• Metabolic: Monitor serum electrolytes regularly.

Patient advice:

• Report any medical history of heart disease, high blood pressure, or kidney or liver disease and current use of any medicines.
• Avoid exposure to chicken pox or measles if on immunosuppressant doses.
• Carry an adequate supply of medication for use in emergencies.
• Notify your physician of dizziness, severe or continuing headaches, swelling of feet or lower legs, or unusual weight gain.

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer