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Efavirenz / Lamivudine / Tenofovir Disoproxil Dosage

Medically reviewed by Drugs.com. Last updated on Nov 30, 2023.

Applies to the following strengths: 600 mg-300 mg-300 mg; 400 mg-300 mg-300 mg

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for HIV Infection

1 tablet orally once a day

Use: As a complete regimen for the treatment of HIV-1 infection

Usual Pediatric Dose for HIV Infection

1 tablet orally once a day

Comments:


Use: As a complete regimen for the treatment of HIV-1 infection

Renal Dose Adjustments

CrCl less than 50 mL/min: Not recommended.

Liver Dose Adjustments

Mild liver dysfunction: No adjustment recommended; careful monitoring recommended.
Moderate or severe liver dysfunction (Child-Pugh B or C): Not recommended.

Dose Adjustments

Concomitant rifampin:

Precautions

US BOXED WARNING:


CONTRAINDICATIONS:

Safety and efficacy have not been established in patients weighing less than 35 kg (Symfi Lo[TM]) or less than 40 kg (Symfi[TM]).

Consult WARNINGS section for additional precautions.

Dialysis

ESRD requiring hemodialysis: Not recommended.

Other Comments

Administration advice:


Storage requirements:

General:

Monitoring:

Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.