Clenpiq Dosage

Important Administration Instructions

• ​Correct fluid and electrolyte abnormalities before administration of CLENPIQ.
• ​CLENPIQ is ready to drink. It is a clear solution with possible presence of visible particles and it does not need to be diluted prior to administration. One bottle of CLENPIQ is equivalent to one dose.
• ​Two doses of CLENPIQ are required for a complete preparation for colonoscopy as a Split-Dose regimen.
• ​The Split-Dose method consists of two separate doses: the first dose during the evening before the colonoscopy and the second dose the next day, during the morning prior to the colonoscopy.
• ​Consume five or more 8-ounce cups of clear liquids after the first dose and four or more 8-ounce cups of clear liquids after the second dose.
• ​Consume a variety of clear liquids. Clear liquids should include balanced electrolyte solution. Additional clear liquids, other than water, include black coffee or tea, plain jello, clear broth or bouillon, clear juices without pulp, ginger ale and other sodas, and frozen juice bars. Do not drink anything colored red or purple.
• ​Consume only clear liquids (no solid food) on the day before colonoscopy and until after the colonoscopy.
• ​Do not eat solid food or dairy and do not drink anything colored red or purple.
• ​Do not drink alcohol.
• ​Stop consumption of all liquids at least 2 hours before the colonoscopy.
• ​Do not take other laxatives while taking CLENPIQ.
• ​Administer oral medications at least one hour before starting each dose of CLENPIQ.
• ​If taking tetracycline or fluoroquinolone antibiotics, iron, digoxin, chlorpromazine, or penicillamine, take these medications at least 2 hours before and not less than 6 hours after administration of CLENPIQ.

Split-Dose Dosage Regimen

The recommended dosage in adults and pediatric patients 9 years of age and older is shown below. Instruct patients to take two separate doses in conjunction with liquids, as follows: