Carbinoxamine Dosage
Medically reviewed by Drugs.com. Last updated on Jun 14, 2024.
Applies to the following strengths: 4 mg; 4 mg/5 mL; 10 mg; maleate-tannate 2 mg-6 mg/5 mL; 6 mg; 1.75 mg/5 mL; 1.5 mg/5 mL; 2 mg/5 mL; 8 mg; 3.6 mg/5 mL
Usual Adult Dose for:
- Allergic Rhinitis
- Allergic Urticaria
- Allergic Reaction
- Allergic Conjunctivitis
- Dermatographism
- Vasomotor Rhinitis
Usual Pediatric Dose for:
- Allergic Rhinitis
- Allergic Urticaria
- Allergic Reaction
- Allergic Conjunctivitis
- Dermatographism
- Vasomotor Rhinitis
Additional dosage information:
Usual Adult Dose for Allergic Rhinitis
Tablet (carbinoxamine maleate 4 mg): 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Tablet, timed-release (carbinoxamine maleate 8 mg): 1 tablet orally every 12 hours
Capsule, extended-release (carbinoxamine maleate 2 mg/8 mg): 1 capsule orally every 12 hours, not to exceed 2 capsules in a 24-hour period
Solution (carbinoxamine maleate 4 mg/5 mL): 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Suspension (carbinoxamine maleate-tannate 2 mg-6 mg/5 mL): 5 mL orally every 12 hours
Liquid (carbinoxamine maleate 4 mg/5 mL): 5 mL orally 4 times a day
Liquid (carbinoxamine maleate 1.5 mg/5 mL): 10 mL orally 4 times a day
Extended release suspension (carbinoxamine tannate 3.6 mg/5 mL): 10 to 20 mL orally every 12 hours
Liquid (carbinoxamine maleate 1.75 mg/5 mL): 10 mL orally 4 times a day
Usual Adult Dose for Allergic Urticaria
Tablet (carbinoxamine maleate 4 mg): 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Capsule, extended-release (carbinoxamine maleate 2 mg/8 mg): 1 capsule orally every 12 hours, not to exceed 2 capsules in a 24-hour period
Solution (carbinoxamine maleate 4 mg/5 mL): 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Suspension (carbinoxamine maleate-tannate 2 mg-6 mg/5 mL): 5 mL orally every 12 hours
Usual Adult Dose for Allergic Reaction
Tablet (carbinoxamine maleate 4 mg): 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Solution (carbinoxamine maleate 4 mg/5 mL): 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Usual Adult Dose for Allergic Conjunctivitis
Tablet (carbinoxamine maleate 4 mg): 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Solution (carbinoxamine maleate 4 mg/5 mL): 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Usual Adult Dose for Dermatographism
Tablet (carbinoxamine maleate 4 mg): 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Solution (carbinoxamine maleate 4 mg/5 mL): 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Usual Adult Dose for Vasomotor Rhinitis
Tablet (carbinoxamine maleate 4 mg): 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Solution (carbinoxamine maleate 4 mg/5 mL): 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Usual Pediatric Dose for Allergic Rhinitis
Liquid (carbinoxamine maleate 1.75 mg/5 mL):
Liquid (carbinoxamine maleate 1.5 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 5 mL orally 4 times a day
>=6 years: 10 mL orally 4 times a day
Liquid (carbinoxamine maleate 4 mg/5 mL):
Suspension (carbinoxamine maleate-tannate 2 mg-6 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 2.5 mL orally 4 times a day
>=6 years: 5 mL orally 4 times a day
Solution (carbinoxamine maleate 4 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 2.5 mL orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Tablet (carbinoxamine maleate 4 mg):
<2 years: Safety and effectiveness unknown
2 to 6 years: 1/2 tablet orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Tablet, timed-release (carbinoxamine maleate 8 mg):
6 to 12 years: 1/2 tablet orally every 12 hours
>=12 years: 1 tablet orally every 12 hours
Capsule, extended-release (carbinoxamine maleate 2 mg/8 mg):
>=12 years: 1 capsule orally every 12 hours, not to exceed 2 capsules in a 24-hour period
Extended release suspension (carbinoxamine tannate 3.6 mg/5 mL):
2 years to 6 years: 2.5 to 5 mL orally every 12 hours
6 years to 12 years: 5 to 10 mL orally every 12 hours
12 years to 18 years: 10 to 20 mL orally every 12 hours
Usual Pediatric Dose for Allergic Urticaria
Suspension (carbinoxamine maleate-tannate 2 mg-6 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 2.5 mL orally every 12 hours
>=6 years: 5 mL orally every 12 hours
Solution (carbinoxamine maleate 4 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 2.5 mL orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Tablet (carbinoxamine maleate 4 mg):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 1/2 tablet orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Capsule, extended-release (carbinoxamine maleate 2 mg/8 mg):
>=12 years: 1 capsule orally every 12 hours, not to exceed 2 capsules per day
Usual Pediatric Dose for Allergic Reaction
Solution (carbinoxamine maleate 4 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 2.5 mL orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Tablet (carbinoxamine maleate 4 mg):
<2 years: Safety and effectiveness unknown
2 to 6 years: 1/2 tablet orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Usual Pediatric Dose for Allergic Conjunctivitis
Solution (carbinoxamine maleate 4 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 2.5 mL orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Tablet (carbinoxamine maleate 4 mg):
<2 years: Safety and effectiveness unknown
2 to 6 years: 1/2 tablet orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Usual Pediatric Dose for Dermatographism
Solution (carbinoxamine maleate 4 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 2.5 mL orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Tablet (carbinoxamine maleate 4 mg):
<2 years: Safety and effectiveness unknown
2 to 6 years: 1/2 tablet orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Usual Pediatric Dose for Vasomotor Rhinitis
Solution (carbinoxamine maleate 4 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 2.5 mL orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Tablet (carbinoxamine maleate 4 mg):
<2 years: Safety and effectiveness unknown
2 to 6 years: 1/2 tablet orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
Antihistamines such as carbinoxamine should not be used in newborn or premature infants.
Reports of excitability in children (i.e. < 18 years) receiving carbinoxamine therapy has rarely been reported.
Antihistamines are more likely to cause dizziness, sedation, and hypotension in elderly patients (i.e. >=60 years). Because of its anticholinergic properties, carbinoxamine meets the Beers criteria as a medication that is potentially inappropriate for use in older adults. Nonanticholinergic antihistamines are preferred in elderly patients when treating allergic reactions.
Dialysis
Data not available
Other Comments
Dosage should be titrated individually depending on patient response and severity of symptoms. The lowest effective dosage should be used to minimize sedation and other adverse effects.
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