Skip to main content

Tenecteplase Disease Interactions

There are 2 disease interactions with tenecteplase.

Major

Tenecteplase -bleeding

Major Potential Hazard, Moderate plausibility. Applicable conditions: History - Cerebrovascular Disease, Hypertension, Brain/Intracranial Tumor, Head Injury

The most common complication encountered during tenecteplase therapy is bleeding. Tenecteplase therapy in patients with acute myocardial infarction is contraindicated in patients with active internal bleeding, history of cerebrovascular accident, intracranial or intraspinal surgery or trauma within 2 months, intracranial neoplasms, arteriovenous malformations or aneurysm, bleeding diathesis or severe uncontrolled hypertension, due to an increased risk of bleeding. Each patient being considered for therapy should be carefully evaluated and anticipated benefits weighed against potential risks associated with therapy.

References

  1. (2001) "Product Information. TNKase (tenecteplase)." Genentech
Moderate

Tenecteplase (applies to tenecteplase) thromboembolism

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Valvular Heart Disease, Arrhythmias

The use of tenecteplase can increase the risk of thromboembolic events in patients with high likelihood of left heart thrombus, such as patients with mitral stenosis or atrial fibrillation. Caution and monitoring is advised.

References

  1. (2001) "Product Information. TNKase (tenecteplase)." Genentech

Tenecteplase drug interactions

There are 152 drug interactions with tenecteplase.

Tenecteplase alcohol/food interactions

There is 1 alcohol/food interaction with tenecteplase.

Report options

Loading...
QR code containing a link to this page

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer