Sodium lactate Disease Interactions
There are 3 disease interactions with sodium lactate.
Alkalinizing agents (applies to sodium lactate) sodium/water balance
Major Potential Hazard, High plausibility. Applicable conditions: Fluid Retention, Congestive Heart Failure, Hypernatremia
Alkalinizing agents containing sodium can induce sodium and water retention and result in hypernatremia, hypokalemia, hyperosmolality, edema and aggravation of congestive heart failure. Therapy with sodium- containing alkalinizing agents should not be used in patients with hypernatremia or fluid retention. Clinical monitoring of acid/base balance and electrolytes prior to, during, a following completion of therapy with alkalinizing agents is recommended.
Sodium lactate (applies to sodium lactate) lactic acidosis
Major Potential Hazard, Moderate plausibility. Applicable conditions: Alkalosis, Liver Disease, Anorexia/Feeding Problems, Shock
Lactate metabolism results in production of bicarbonate. Bicarbonate generation is impaired in patients with compromised liver function and/or disorders that decrease tissue perfusion and increase anoxia. Therapy with sodium lactate should not be used in conditions in which lactate levels are increased (e.g., shock, congestive heart failure, respiratory alkalosis) or in which utilization of lactate is diminished (e.g., anoxia, beriberi). Sodium lactate is not for use in the treatment of lactic acidosis.
Alkalinizing agents (applies to sodium lactate) acid/base balance
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Alkalosis, Renal Dysfunction
Alkalinizing agents act as proton acceptors and/or dissociate to provide bicarbonate ions. Elimination of bicarbonate is decreased in patients with renal impairment and can result in metabolic alkalosis. Symptoms of metabolic alkalosis include hyperirritability or tetany, arrhythmia, and/or seizures (altered pH = altered calcium), or lactic acidosis due to impaired oxygen release. Therapy with alkalinizing agents should be administered with extreme caution in patients with compromised renal function. Clinical monitoring of renal function, acid/base balance and electrolytes is recommended.
Sodium lactate drug interactions
There are 33 drug interactions with sodium lactate.
More about sodium lactate
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
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