Mannitol Disease Interactions
There are 2 disease interactions with mannitol.
Osmotic diuretics (applies to mannitol) fluid overload
Major Potential Hazard, Moderate plausibility. Applicable conditions: Congestive Heart Failure, Pulmonary Edema, Anuria, Dehydration
The use of osmotic diuretics is contraindicated in patients with anuria, severe dehydration, pulmonary edema, or severe cardiac decompensation. An increase in the tonicity of the blood may occur in these patients that could exacerbate these conditions.
Osmotic diuretics (applies to mannitol) hyperosmolar effects
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease, Psychosis, Diabetes Mellitus, Renal Dysfunction
The use of osmotic diuretics is associated with an increase in blood tonicity. Osmotic diuretics should be administered cautiously in patients with confused mental states, diabetes, congestive heart failure, severe dehydration, and cardiac, renal, or hepatic disease.
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Mannitol drug interactions
There are 136 drug interactions with mannitol.
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- Drug class: miscellaneous diuretics
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
