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Lindane topical Disease Interactions

There is 1 disease interaction with lindane topical.

Major

Lindane topical (applies to lindane topical) seizure disorders

Major Potential Hazard, High plausibility. Applicable conditions: Seizures, Prematurity/Underweight in Infancy

The use of lindane is contraindicated in patients with seizure disorders. Topically applied lindane is systemically absorbed and has induced CNS toxicity such as dizziness, headache, disorientation, and seizures. Although seizures have generally occurred due to product misuse or oral ingestion, they have also been reported occasionally when used as directed. Lindane use is also contraindicated in premature neonates due to the likelihood of increased skin permeability.

References

  1. Tenenbein M (1991) "Seizures after lindane therapy." J Am Geriatr Soc, 39, p. 394-5
  2. Pramanik AK, Hansen RC (1979) "Transcutaneous gamma benzene hexachloride absorption and toxicity in infants and children." Arch Dermatol, 115, p. 1224-5
  3. Matsuoka LY (1981) "Convulsions following application of gamma benzene hexachloride." J Am Acad Dermatol, 5, p. 98-9
  4. "Product Information. Kwell (lindane)." Reed and Carnrick, Jersey City, NJ.
View all 4 references

Lindane topical drug interactions

There are 178 drug interactions with lindane topical.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

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